I have the same problem. There is always about 1/4 of the bottle left in. I don't discard the leftover amount. Instead, I save the amount that remains and pour it into the bottle that has 1/4 left. Therefore, I feel I don't waste it.
The best postition for me is to kneel with my butt in the air...not a pretty sight, but I make sure I am by myself in the bedroom while doing this....and stick it in. Try remaining in that position for a few minutes. Then I lie on my side. Sometimes it stays in and sometimes I can only hold it for a short while. I take Canasa suppositories in the mornings. I have better luck retaining them than the cort enemas.
Diagnosed with ulcerative proctitis in 1998 in hospital
Hospitalized (2nd time) in May 2008 for ten days.
Remission Nov 08 thru May of 09.
Slowly coming out of flare. Meds: Colazal (6 per day), prednisone 10 mgm and tapering weekly, Cort enema nightly, Canasa in morning, Benicar 20 mg for BP, flaxseed oil 3 x a day, fishoil 2 x a day, probiotic 3 x a day, calcium with D 1x a day and multivitamin.
Doctor had me on 100 mgm of 6MP which drastically lowered my white count. Now off the 6MP pending results of repeat white count. UGH.