Hi FG....you definitely need to be on rectal meds to deal with that inflammation. The Lialda isn't enough.
I don't know in truth which was first, but my LFTs didn't increase to the point of concern until about
11 years ago.
Diarrhea with your mom could be from the fact that she has PSC I think, maybe the URSO as well...what's her dosage?
It's possible that one inherits the disease....I have no idea if others in my family have/had it.
I'm hardcore 5ASA meds, and I believe that keepping the colon in as low inflammation as possible is what can help the PSC in a quiet state as well. I'm still in early stages and the LFTs have been continually normal since starting the URSO about
5 years ago (I think..have to check on that).
I think I would pass on the immunosuppressants and the pred and prefer to have my colon out if the 5ASA meds stopped working for me.
I don't drink except for a nip of wine occasionally.
I do take tylenol once a day at least....some say it's a huge NO for the liver...sigh....
I do drink coffee, however, which I've read is good for the liver...so that's a plus.
I did take milk thistle, but don't anymore...no reason except it's one less thing to take.
Call the doc or go and get on rectal meds...I would suggest the Rowasa (if you're in the US)
You won't be able to stop the PSC if it's on its way, but please don't have an ERCP if it's ever suggested. You might want to ask your doc if he can set you up eventually for a MRCP to see if you are in early stages. You might have legit claim considering your mom has it....how sad she does.
It takes a while to get the UC flares/meds worked out.
*Heather* Status: ...Asacol 3 twice daily; Salofalk enemas every 3rd night
~diagnosed January 1989 UC (proctosigmoiditis)
~UC meds: Asacol (3 @ 2x daily); Salofalk enemas nightly for flares & taper to maintenance
~Bentylol (dicyclomine) 20mg as needed; Ranitidine (reflux); Effexor XR 75mg(depression); Pulmicort/Airomir (asthma)
~vitamins/minerals/supplements; Probiotics....(RenewLife Ultimate Flora Critical Care + Primadophilus Reuteri). @ bedtime
~various digestive enzymes as needed
~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS" worth it !!!