The bad bacteria finally found?

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chezzyman
Regular Member


Date Joined Sep 2008
Total Posts : 45
   Posted 8/27/2009 10:45 AM (GMT -6)   
I've just found this article, looks very interesting, I don't know if it is somehow connected with UC, but if it causes inflamation of the colon, it might be.. http://www.telegraph.co.uk/health/healthnews/6069108/Scientists-discover-bacteria-which-causes-colon-cancer.html
UC (Proctosigmoiditis) april 2008
Prednisone 25mg
Asacol 3x3
Asacol enema every second night
colon dophilus probiotics
 
-
flare up


hedgehog
Regular Member


Date Joined Jul 2007
Total Posts : 102
   Posted 8/27/2009 11:04 AM (GMT -6)   
Interesting article. Thanks for posting funkyskank!

Tara
Ottawa, Ontario, Canada
-F/33 -diagnosed June 2006
-last 25cm of colon affected
-xylocaine enemas put me in remission
-Asacol 2 800mg pills 2x/day
-budesonide enemas every 4-5 days


mindstyle
Regular Member


Date Joined Aug 2009
Total Posts : 62
   Posted 8/27/2009 11:22 AM (GMT -6)   
If anybody is interested in the scientific literature of this article, its http://www.nature.com/nm/journal/vaop/ncurrent/abs/nm.2015.html, (subscription required for full text.) Certainly interesting!!
Diagnosed with Ulcerative Colitis since 2006, at the age of 30 years

Currently taking
100mg of Azathiprine, twice a day
2250mg of Balsalazide Hydrochloride, 3X a day
10mg of Vit. B12, once a day
500mg Salazopyrine suppository once a day.

30mg/day of Prednisolone since 2009/08/21 to control recent flare up, will reduce the dose by 5mg each week. (hoping not to swell up)


GLOVE
Regular Member


Date Joined Jul 2009
Total Posts : 321
   Posted 8/27/2009 12:14 PM (GMT -6)   
Very interesting...thank you!
UC since 2002- remission for 6 years
recent flare 06/09
Currently on Colazal, multivitamin, probiotics, fish oil
just tapered off prednisone
 


quincy
Elite Member


Date Joined May 2003
Total Posts : 31006
   Posted 8/27/2009 1:41 PM (GMT -6)   
It's a different type of inflammation, however, and UC is a different response. Not to say both cannot happen together.
 
Remember that the mice are bred genetically to be predisposed to cancer.  Another important link.
 
Thanks for the link...very informative.
quincy


*Heather* Status: ...Asacol 3 twice daily; Salofalk enemas every 3rd night
~diagnosed January 1989 UC (proctosigmoiditis)
~UC meds: Asacol (3 @ 2x daily); Salofalk enemas nightly for flares & taper to maintenance 
~Bentylol (dicyclomine) 20mg as needed; Ranitidine (reflux);  Effexor XR 75mg(depression);  Pulmicort/Airomir (asthma) 
~vitamins/minerals/supplementsProbiotics....(RenewLife Ultimate Flora Critical Care + Primadophilus Reuteri). @ bedtime
~various digestive enzymes as needed
~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS"  worth it !!!
 


walker40
New Member


Date Joined Aug 2009
Total Posts : 6
   Posted 8/27/2009 1:50 PM (GMT -6)   
Thanks for the article!! When my daughter was diagnosed at age 4 with UC (now almost 11) her GI at the time said that if they did not find a cure for UC in the next 10 years that she would probably have to have her colon removed because of the risk of Colon Cancer. Great, right? We changed GI's shortly thereafter. Anyway, I was in my doctor's office crying, telling him what her GI had said and he told me that it was not true, and that years ago they though Ulcers were caused by stress, and have since learned that they are caused by a bacteria, and that one day they will probably discover that IBD is caused by a bacteria too. I've always keep those words in my mind, especially given my daughter's history with her UC. I'm convinced hers may have to do with some type of bacteria. It sounds like from that article that my doctor could be right! I'll have to send him the article. Thanks again.

mindstyle
Regular Member


Date Joined Aug 2009
Total Posts : 62
   Posted 8/27/2009 2:23 PM (GMT -6)   
PLEASE, Take all the information presented to you with a pinch of salt, may it be by your GI or may it be by popular science. Yet, nobody knows what is the cause of ulcerative colitis and since 50s UC is called as stress disorder. The efforts are made on wide fronts to figure out what is going on but human is a complex organism to work with and there are so many pathways criss-crossing, its hard to pinpoint. If anybody is interested, I can give pointers to scientific evidence and the work in progress at the moment.
Parallel work is also going on using dogs, as they are most prone to UC.

Every treatment is not as simple as killing the bacteria.
Diagnosed with Ulcerative Colitis since 2006, at the age of 30 years

Currently taking
100mg of Azathiprine, twice a day
2250mg of Balsalazide Hydrochloride, 3X a day
10mg of Vit. B12, once a day
500mg Salazopyrine suppository once a day.

30mg/day of Prednisolone since 2009/08/21 to control recent flare up, will reduce the dose by 5mg each week. (hoping not to swell up)


bbc
Veteran Member


Date Joined Mar 2008
Total Posts : 1580
   Posted 8/27/2009 8:00 PM (GMT -6)   
If possible, would you be kind enough to summarize the work in progess info?
Thanks
mindstyle said...
PLEASE, Take all the information presented to you with a pinch of salt, may it be by your GI or may it be by popular science. Yet, nobody knows what is the cause of ulcerative colitis and since 50s UC is called as stress disorder. The efforts are made on wide fronts to figure out what is going on but human is a complex organism to work with and there are so many pathways criss-crossing, its hard to pinpoint. If anybody is interested, I can give pointers to scientific evidence and the work in progress at the moment.
Parallel work is also going on using dogs, as they are most prone to UC.

Every treatment is not as simple as killing the bacteria.


Dx'd with moderate Pancolits 05/07 better with Pentasa and Cortifoam.
I also take Probiotics, Curcumin, Benefiber and cannot tolerate
artificial sweetners (never could even before UC).
 
 
UC Forum Co-Moderator
I am not a healthcare provider. I am offering support and guidance based upon my own conclusions and/or research. ALWAYS consult with a qualified healthcare provider.


jeanneac
Veteran Member


Date Joined Feb 2009
Total Posts : 1916
   Posted 8/27/2009 9:24 PM (GMT -6)   
If I remember my microb iology, that type of bacteria, bacteroides, is a normal flora bacteria in the intestines. I wonder how they decided it had a role in colon cancer? They didn't elude to that in the article. I am sure it is way more complicated than that or we'd all have it.
diagnosed 1/09 with "diverticular colitis" ?? location, sigmoid colon
localized scleroderma & IBS, low thyroid
 50 +  female
 colazal, fish oil, synthroid, zoloft, VSL#3 probiotic.
Blood test positive for Crohn's for whatever that is worth-:)
 


mindstyle
Regular Member


Date Joined Aug 2009
Total Posts : 62
   Posted 8/28/2009 1:50 AM (GMT -6)   
@ bbc,

Sure I will, just give me some days. After reading through these forums, I was seriously considering it anyways. I am strongly suspicious that many posters here are acting out of information obtained from popular science articles, that sometimes lack solid scientific evidence. I will make such article and post it as soon as possible.

Thanks for your interest.
Diagnosed with Ulcerative Colitis since 2006, at the age of 30 years

Currently taking
100mg of Azathiprine, twice a day
2250mg of Balsalazide Hydrochloride, 3X a day
10mg of Vit. B12, once a day
500mg Salazopyrine suppository once a day.

30mg/day of Prednisolone since 2009/08/21 to control recent flare up, will reduce the dose by 5mg each week. (hoping not to swell up)


LuckyLindy
Regular Member


Date Joined Feb 2009
Total Posts : 226
   Posted 8/31/2009 1:19 AM (GMT -6)   
Articles like this make me want to just take a whole bunch of antibiotics and then do a fecal transplant. I have all the materials (3 types of antibiotics, blender, coffee filters, enema equipment, etc), just not the guts to try it yet (doctor would probably drop me if he knew).
33 year old male
diagnosed severe pancolitis in 2004, unresponsive to all drugs
turned down recommendation to have j-pouch surgery
have been mostly symptom free since 2004 via diet modification (removed all carbs)


subdued
Veteran Member


Date Joined Dec 2008
Total Posts : 3231
   Posted 8/31/2009 5:54 AM (GMT -6)   
I skipped taking the antibiotics and just did the fecal transplantation part. It was the best thing I ever did for my colon. I told my GI. He thinks I'm just lucky. He wanted me to be on maintenance medicine, but after having only one flare in three years (which I got after being on antibiotics), he's fine with my not taking any maintenance medicines.
Joy - 47 yrs and counting; Dx Colitis Dec 06 (also had IBS); Currently in remission

Figuring out how to reduce a flare or get into remission is a trial and error experience. Don't expect your GI to have all the answers. He was trained in making diagnoses, prescribing medications, and surgically removing the colon. He was not trained in alternative treatments. That's why they are called alternative treatments.

What works for me: Fecal transplantation, Probiotics, Anti-inflammatory foods, No HFCS, No foods high in fructose, No artificial sweeteners, No pro-inflammatory foods when flaring, Vitamins, Lexapro (for stress).


songlady
Veteran Member


Date Joined Aug 2009
Total Posts : 3698
   Posted 8/31/2009 6:52 AM (GMT -6)   
In this bacteria discussion, it might be interesting to note this from the ccfa website, about the researcher who found the good bacteria that protects from UC:
http://www.ccfa.org/about/press/pressreleases/Scholaraward

We live in exciting times, research-wise. I am positive there is some bacteria that is the trigger for this, even if one is genetically predisposed. Time will tell. But - when I was first diagnosed, I didn't think any answers would come within my lifetime, and now it looks as though they well might!
Diagnosed UP 1983, Azulphidine
Diagnosed UC 1986 Prednisone almost 2 years
Asacol - 16 pills a day
Metamucil - 2 doses a day
Cortenemas or Rowasa from time to time
VSL#3, Ultimate Flora Critical Care
Canasa as needed

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