xTMx..welcome to the forum!
Are you wanting to just get off the 6MP or all the meds? If you can use the Apriso, that's great...you should, however, be on rectal meds as well.
I've used the 5ASA meds, oral/rectal for over 20 years. Who knows what'll be available in the time you will be on them....
5ASA is still the one med with the least side effects if you can take salicylates. You can taper to a lower dosage if you need to, but in reality if you can deal with and limit your flares in the distal part of your colon initially (rectum/sigmoid) than you can head off more serious flares and probably from going higher into your entire colon.
The goal is to keep everything as quiet as possible. If you can achieve that with the first-line meds, that will be a good thing.
It does take commitment, however, which sucks sometimes.
*Heather* Status: ...Asacol 3 twice daily; Salofalk enemas every 3rd night
~diagnosed January 1989 UC (proctosigmoiditis)
~UC meds: Asacol (3 @ 2x daily); Salofalk enemas nightly for flares & taper to maintenance
~Bentylol (dicyclomine) 20mg as needed; Ranitidine (reflux); Effexor XR 75mg(depression); Pulmicort/Airomir (asthma)
~vitamins/minerals/supplements; Probiotics....(RenewLife Ultimate Flora Critical Care + Primadophilus Reuteri). @ bedtime
~various digestive enzymes as needed
~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS" worth it !!!