Has anyone taken Benedryl while having a flare up?

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Regular Member

Date Joined Aug 2009
Total Posts : 94
   Posted 8/31/2009 6:58 AM (GMT -6)   
My dd broke out in hives all over her side and arm and my doctor said it was ok to give her Benedryl. Well I did last night and she wound up going every half hour. She's been up since 2 am going bad diarrhea and blood. she's been going to through a bad flare for the past week but she was only going every 1-2 hours. Last night was the worst and I was just wondering if it was the Benedryl?
Did anyone else have a bad experience with Benedryl..especially in young children. My child is 3 years old.
thank you

Regular Member

Date Joined Dec 2008
Total Posts : 274
   Posted 8/31/2009 12:42 PM (GMT -6)   
I haven't taken benadryl since my actual diagnosis, but shortly before, while I was having lots of D, I had to take some. Also was for hives. I don't remember it bothering me.

Chuck - 28 yrs and counting
Diagnosed w/ UC Dec 08 - pancolitis
Pentasa 500mg 2pills-4x daily
Prednisone 50mg Calicium + Vit D
Multivitamin, vitamin C, probiotics, fish oil
"If you can solve your problem, then what is the need of worrying? If you cannot solve it, then what is the use of worrying?"

Elite Member

Date Joined Feb 2004
Total Posts : 20577
   Posted 8/31/2009 12:59 PM (GMT -6)   
Yes it's safe, I've heard that using antihistamines like benedryl can actually aid with IBD symptoms cuz of our immune systems being array (they don't know if it's over or underactive so they just say it's impaired) but many actually find some relief using antihistamines for their IBD...I tried it myself but didn't notice any difference.

My bum is broken....there's a big crack down the middle of it! LOL :)

Veteran Member

Date Joined Jul 2008
Total Posts : 823
   Posted 8/31/2009 1:40 PM (GMT -6)   
I have taken it with no problems. In fact it sometimes seems to help slightly. My daughter is also three. She does not have UC but has taken Benedryl a few times before. It has not bothered her. Do you know what caused the hives to start with? Sometime viral infections or colds can cause hives on children and the diarrhea might be from both UC and a viral infection too...just a thought...I don't know where you live but in Texas we are already seeing some of the typical fall viral infections start to pop up...which is early for us this year...
Dx 2006 right after the birth of my daughter
Lialda 2 pills a day
Cort-enemas as needed
Canasa as needed
Probiotics Daily

Elite Member

Date Joined May 2003
Total Posts : 30993
   Posted 8/31/2009 10:16 PM (GMT -6)   
The Benadryl shouldn't have caused her to have any serious side effects that would have caused her to have diarrhea unless she's sensitive to a product in the medication.

What form of the Benadryl did you give her? There is sucralose in some of the formulas.

The hives could have been a symptom of possibly a food allergy.....hence the diarrhea.

What did she eat during the day?

What other meds is she on at this time?

How about vitamins...? or other supplements?

It's possible you may have to get her in to see an allergist if she's exhibitted hives...could be the beginning of something else going on.

Did the Benadryl help the hives?

How is she at this time?

Hope this is a short-term thing.

Oh, is she also on probiotics?

*Heather* Status: ...Asacol 3 twice daily; Salofalk enemas every 3rd night
~diagnosed January 1989 UC (proctosigmoiditis)
~UC meds: Asacol (3 @ 2x daily); Salofalk enemas nightly for flares & taper to maintenance 
~Bentylol (dicyclomine) 20mg as needed; Ranitidine (reflux);  Effexor XR 75mg(depression);  Pulmicort/Airomir (asthma) 
~vitamins/minerals/supplementsProbiotics....(RenewLife Ultimate Flora Critical Care + Primadophilus Reuteri). @ bedtime
~various digestive enzymes as needed
~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS"  worth it !!!

Regular Member

Date Joined Aug 2009
Total Posts : 94
   Posted 9/1/2009 9:27 AM (GMT -6)   
thank you all for your responses. I was blaming the Benedryl for her flare getting worse, but in reality it was just a really bad night. Last night was better and we gave her the Benedryl. she is just going through a really bad flare and the Pred. that she is on is not working. We just came back from the doctor and he feels the rash is probably going away. Maybe it will take a few more days but it should be gone by the end of the week. He also told us to up our Cortifoam to 3-4x a day. That is the only thing giving her relief at the moment. At least that gives us a break for a few hours. I did give her some probiotics and I do believe that could have made it worse. I've since put her on a very simple diet. Just things that she's been eating since she was a baby. Nothing new at all, so if it is an allergic reaction it should be gone in a few days.

thanks again for all your responses.

Veteran Member

Date Joined Jul 2008
Total Posts : 823
   Posted 9/1/2009 10:09 AM (GMT -6)   
I am so sorry to hear that she is in such a bad flare. It is one thing for me as an adult to go through that but it is entirely different for a three year old. My thoughts are with you! I hope she can get out of this flare soon!
Dx 2006 right after the birth of my daughter
Lialda 3 pills a day
Cort-enema nightly
Canasa in the morning
Probiotics Daily

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