Abatacept Clinical Study Trial - Cancelled

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Regular Member

Date Joined Jan 2006
Total Posts : 479
   Posted 9/5/2009 8:22 AM (GMT -6)   
The Abatacept trial for Ulcerative Colitis that I have been on for the past 2 years has suddenly been dropped.  I was doing quite well on the trial, so I am very disappointed.
Apparently, early analysis has indicated that the drug is no more effective than placebo.  Severe reactions were also cited.  So, everyone, including me, are all now off the trial with immediate effect :(
I don't know what I will do next.  I have tried every other UC drug out there. I just hope I can get onto a different trial.
Very worried now about what the future holds in store.

Pan UC - 9 yrs
Prednisolone 3.5mg
Azathioprine 150mg
Colazide 9x 750mg

Veteran Member

Date Joined Jul 2006
Total Posts : 2105
   Posted 9/5/2009 9:44 AM (GMT -6)   
Golimumab trial seems to be going pretty well from what I see. Only thing I disagree with is the way its administered. I had more success with it when it was given like remi is, they dropped that and dose it like humira now. No side affects. There was a few others on it here, but they disappeared. I assume they got better, lol.

MLN02 is a very promising trial that I will go into next if this one doesn't give me complete remission. Seems safe. (http://www.healingwell.com/community/default.aspx?f=38&m=1560078)

Hope you live near a research hospital.
Proctitis DX 1999, Pancolitis DX 2008
Golimumab study (100mg every 4 weeks)
L-Glutamine 5000 mg + 600 mg pyridoxal alpha-ketoglutarate
Probiotis/VitD3 5000IU+Ca/1000mg DHA

Forum Moderator

Date Joined Dec 2008
Total Posts : 16736
   Posted 9/5/2009 11:17 AM (GMT -6)   
That is very frustrating. I can imagine how you feel.. My doctors office is playing a lot of games with the refill of my prescription for Asacol and I know I am going to run out before we get through all the red tape. It is stressing me out so badly.
Diagnosed with mild proctitis in March 2007: Treated with Canasa (as needed)
Horrible relapse: August 08 - December 08: Began treating with Asacol 400mg (9/day) + Canasa 2x/day - Anemic
Canasa nightly + Asacol (9/day) + Probiotics + Iron

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