That's weird, because when I used Culturelle, the store I bought it from kept it refrigerated, and I think the box said it's best to do it, but it's not required.
Status: Remission since May 2009!
Symptoms began in November 2008, ~4 weeks after giving birth to my son
Diagnosed with pancolitis on 1/30/09
Meds: Apriso (4 0.375g pills ONCE!! daily), mesalamine enema twice weekly, Natural Factors Ultimate probiotic 12/12 Formula, OrthoNovum, multivitamin. Used prednisone (starting dose 40 mg) to get into remission.
Thread with links to UC resources and information: