Any one on Sulfasalazine

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jano437
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Date Joined Jul 2005
Total Posts : 1614
   Posted 12/23/2009 12:22 PM (GMT -6)   
I have ulcerative colitis and arthritis and my rhematologist is trying to treat both with one med. The first of the year he is putting me on Sulfasalazine. Is anyone on here taking this? I would love to hear the good and bads of this and any suggestions you have for me while taking this. Thank you
Diagnosed July 2005 with Pancolitis
Asacol 4 tabs 3 times daily
Pro-Bio
Forvia
calcium


Dr-A
Veteran Member


Date Joined Jul 2006
Total Posts : 2105
   Posted 12/23/2009 12:24 PM (GMT -6)   
I actually just switched myself back to it yesterday. Was first drug I took around 10-11 years ago but didn't stay on it too long. Waiting to see what side affects may come.
Proctitis DX 1999, Pancolitis DX 2008
L-Glutamine 5000 mg + 600 mg pyridoxal alpha-ketoglutarate
Probiotis/VitD3 5000IU+Ca/1000mg DHA


seconder
Veteran Member


Date Joined Jun 2008
Total Posts : 610
   Posted 12/23/2009 1:12 PM (GMT -6)   
I take sulfasalazine, best drug I've ever taken. A few transient side effects at first, but you can start at a low dose and work up to minimize them. At this point, no real side effects to speak of, a little photosensitive, a touch of ringing in my ears every once and awhile.

I requested the shift to sulfasalzine because of joint pain. First time in 12-15 years I haven't had crippling pain in my knees.

jano437
Veteran Member


Date Joined Jul 2005
Total Posts : 1614
   Posted 12/23/2009 1:38 PM (GMT -6)   
Seconder, I have a question about the photosensitive. I am planning on going to the beach this summer. Do you think there is going to be a problem with this, or any suggestions
Diagnosed July 2005 with Pancolitis
Asacol 4 tabs 3 times daily
Pro-Bio
Forvia
calcium


ickypoo
Regular Member


Date Joined Dec 2008
Total Posts : 224
   Posted 12/23/2009 2:42 PM (GMT -6)   
I have been using sulfasalazine for about 20 years now. The only problem I have had is the occasional bout of nausea. Switching to the enteric form of the medication eliminated that for the most part. The only other time I have felt a little wobbly was when I was taking fairly high doses (in the 4 grams/day range). But I am on such a low dose now (1 gram/day), that I have no problems at all.
Diagnosed with UC in 1990.
Current Meds: Sulfasalazine & Folic Acid.
Supplements: fish oil, flax oil, glucosamine, CoQ10, fiber, aloe vera juice, probiotics.
Other: unpasteurized milk every day.


seconder
Veteran Member


Date Joined Jun 2008
Total Posts : 610
   Posted 12/23/2009 3:47 PM (GMT -6)   
Well, I've tried to use the quote function to no avail.
 
Jano:  My eyes are photosensitive, so I wear sunglasses, and I usually lather on the sunscreen and wear a shirt at the beach.  Still, after a trip to the beach last year, when I got back to work, someone remarked, "You look like a yam!"
 
 

Malkavian
Veteran Member


Date Joined Mar 2009
Total Posts : 1439
   Posted 12/23/2009 3:56 PM (GMT -6)   
I'm fairly certain princesa is on it as well. I was considering taking it at some point and then found out I couldn't because of an allergy to sulfa antibiotics.
22, female, diagnosed 3/6/2009, symptoms for 2 years beforehand
Mild ulcerative colitis from rectum to mid transverse colon
Currently on lialda 2/day, rowasa, calcium and d, B12, and probiotics
Things that help: probiotics, omega 3's, oral 5-ASAs, low fiber when flaring, soluble fiber, low saturated fat diet
Things that hurt: insoluble fiber, fried or spicy food, caffeine, alcohol, rectal meds when not flaring


nightside of eden
Veteran Member


Date Joined Sep 2009
Total Posts : 552
   Posted 12/23/2009 4:05 PM (GMT -6)   
I have been on it for 15 years....I have had no side effects....The drug has worked wonders for me, up until a few years ago, when i started to have mini flares, but it kept me in remission for over 10 years.....The one problem I had with it, was that it wouldn't control my arthritis very well, so i take Humira now with the sulfasalizine, and i have no joint pain ever anymore. Its a good drug though.

JewelsOK
Regular Member


Date Joined Jun 2007
Total Posts : 364
   Posted 12/23/2009 4:44 PM (GMT -6)   
My son took it for 7 years and did well on it. The last 6 months he was on it he started getting almost daily headaches and had to switch Lialda. At high doses (6 grams daily) he would sweat with a yellow-orange tint.

When my youngest was dx doctor put her on it since her brother did so well, but she developed a rash (likely allergic) so it's a no go for her.

It's a great drug and very affordable!

Let us know how you do on it. Good luck!
Julie

Mom of Son 18 UC dx 07/02, Lailda, Azasan 100 mg, Primadophilus Reuteri, Zyrtec, Iron, Vit/Min

Daughter 10 UC dx 08/07 Prednisone 5 mg, Colazal, 6MP 25 mg, Culturelle, Iron, Vit/Min.


jano437
Veteran Member


Date Joined Jul 2005
Total Posts : 1614
   Posted 12/24/2009 11:45 PM (GMT -6)   
Thanks everyone for your advice
Diagnosed July 2005 with Pancolitis
Asacol 4 tabs 3 times daily
Pro-Bio
Forvia
calcium


Old Hat
Veteran Member


Date Joined Feb 2007
Total Posts : 5191
   Posted 12/25/2009 12:02 AM (GMT -6)   
I took the enteric-coated (EN-tabs) variety in my early yrs with UC; that prevented stomach upset. It made me a bit headachy at 1st-- the gastro told me to start with one tablet per dose for a couple days & then increase to 2 per dose, etc. to see if my body could tolerate sulfa. The main reasons I wanted to get off it came from photosensitivity. I could slap on sunscreen-- that wasn't a big deal, but I didn't like the effect on my eyes. Also, I think it altered my sense of taste somewhat. But you may find it helpful-- Princesa seems to be doing very well on it for a good while now. And it's the cheapest oral 5-ASA, woo-hoo! / Old Hat (30 yrs with left-sided UC ... [etc.)

munchkindd
Regular Member


Date Joined Oct 2007
Total Posts : 348
   Posted 12/29/2009 7:41 PM (GMT -6)   
Yes, I am on it.  It works better than anything else for me.  Have never really had any problems with it.  It definitely helped with my arthritis.  I was off this medication for several years and really noticed alot more arthritis pain.  Drink a large glass of water with each dose. You have to have blood work done every few months while on this. This is alot cheaper than the expensive stuff I tried (which didn't work for me)  I know alot of people can't take it because of the sulfa.   Good Luck!  Hope it works for you.

*******Donna*******
 
South of Boston, Ma
 
diagnosed with uc 27 years ago.  Enojoyed 20 year remission with just minor blips here and there (approximately 16 of those years without any meds)
 
In a flare for 2 very long years which Asacol didn't help at all.  Finally in remission again since Jan 2008, can't believe it..............
 
currently on Sulfasalazine 2 tabs 3x day. Folic acid, mesalamine enema once a week. Omega 3, Probiotics, multi vitamin, calcium supplement, Biotin 5000mcg, Fibercon.
 


Dr-A
Veteran Member


Date Joined Jul 2006
Total Posts : 2105
   Posted 12/29/2009 10:38 PM (GMT -6)   
Been back on it for little over week now. Not using the enteric coated ones, but I don't notice any side affects yet. Also don't notice the worsening of D, as with the colazal and lialda....... Not sure why in the world my doc did not suggest this. Eventually, I may find a GI doc that knows how to treat me better than I do.
Proctitis DX 1999, Pancolitis DX 2008
L-Glutamine 5000 mg + 600 mg pyridoxal alpha-ketoglutarate
Probiotis/VitD3 5000IU+Ca/1000mg DHA


Delarge
Regular Member


Date Joined Mar 2007
Total Posts : 157
   Posted 12/29/2009 11:38 PM (GMT -6)   
I've been using 2 grams daily for almost a year at this point and overall I'm pleased with its efficacy. I experienced mild headaches initially, however those subsided after approximately one month. I'd recommend supplementing with folic acid, as sulfasalazine is known to impair absorption.

Red_34
Elite Member


Date Joined Apr 2004
Total Posts : 23551
   Posted 12/30/2009 7:54 AM (GMT -6)   
Yes Janice, wear sunscreen when you get out in the sun because you will burn easier while on Sulfasalazine. If taken for a long time, it can also give you a slight yellowish cast to your skin. At least is did for me and I am fair skinned with freckles. I was on it for about 6 months or so but had to stop due to an allergic reaction (welts and hives). It helped my Uc a lot but I didn't have arthritis at that time.
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~Left sided Uc-'92-Colazal(6 daily),6mp(50-100mgs),Bentyl, Prilosec,Biotin,Forvia,Pro-Bio**Unable to tolerate ALL mesalamines**~Allergies-Singulair, Zyrtec~Secondary Reynauds Syndrome-Norvasc~Sacroiliitis~bulging and herniated discs C5/C6 & C6/C7~Epidural injections (2 series of 3), OA-Tylonel Arthritis
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IndianaUC
Regular Member


Date Joined Feb 2007
Total Posts : 212
   Posted 12/30/2009 2:12 PM (GMT -6)   
I've been taking 4grams of Sulfasalazine since the fall of '07. I had horrible headaches at first that lasted a couple of weeks, but since then I've done just fine. The sulfa tends to rob the body of Folic acid and sunshine will do the same so you're losing it twice as fast then. I take extra folic acid every day I can remember. The sulfa can also bind with it and make the sulfa ineffective(so I'm told) so I have to wait 2hrs before taking the folic acid. All last summer I tanned in the yard and didn't burn at all, but I tanned quite well. My tan seems to be lasting more than I remember before, but with my iron so low it's hard to remember much of anything these days. Overall I'd say that I plan to stay on the Sulfa for as long as I can. For me besides the initial headaches, yellow/orange urine seems to be my only side effect.
- DXed with "left sided" UC in 1998. DXed with "proctitis" Oct. 2007
- Sulfasalazine 4 500mg tabs twice daily
- 500mg Vitamin C, 1 Multivitamin, L-Glutamine
- Max Acidophillis EC Capsules 350Mg(7 types of bacteria with over 42 billion viable cells) with 50 Mg colostrum & 50 Mg FOS(fructo-oligosaccharides)
- Experimenting with this or that on occasion. Always open to new ideas.
- Colonoscopies - 2 (Due for my next one ASAP)
- Canasa 1000mg @night. Started Oct. 23, 2008
- Niferex-150 Forte 1 capsule 2x Daily


ednort
New Member


Date Joined Dec 2009
Total Posts : 10
   Posted 12/30/2009 3:48 PM (GMT -6)   
Just started about 15 days ago 500mg 3x day. NO good results yet but no side effects. How long does this stuff take to start working for mild case of UC??

jano437
Veteran Member


Date Joined Jul 2005
Total Posts : 1614
   Posted 12/31/2009 5:04 AM (GMT -6)   
I am not sure ednort, i haven't started taking it yet, but some say a few days, and some say a few weeks. I guess everyone is different
Diagnosed July 2005 with Pancolitis
Asacol 4 tabs 3 times daily
Pro-Bio
Multivitamin


KOB821
New Member


Date Joined May 2009
Total Posts : 7
   Posted 1/1/2010 3:40 AM (GMT -6)   
I have been taken it for almost 3 years 500mg x 8 per day. The two major side effects are migraines and bright yellow urine. It work on the first 2 years then it stop. I am starting remicade next week hopefully my body can tolerate it. My GI said even if I can tolerate remicade I should still keep 2 tablets per day to lower to risk of colon cancer. Don't take it will 6MP it will increase your risk of headaches.
26 yrs female.
Diagnosed 24yrs old. Jan 07.
Sulfazine EC 500mg 2 tablets/ 4x


jano437
Veteran Member


Date Joined Jul 2005
Total Posts : 1614
   Posted 1/1/2010 8:59 PM (GMT -6)   
I hear a lot of migraines and headache side effects. Does taking tylenol take care of it, or is the headache to strong for it
Diagnosed July 2005 with Pancolitis
Asacol 4 tabs 3 times daily
Pro-Bio
Multivitamin


Old Hat
Veteran Member


Date Joined Feb 2007
Total Posts : 5191
   Posted 1/1/2010 9:56 PM (GMT -6)   
The key to combatting headaches, I found, is what Munchkindd advised above: drink plenty of water. Otherwise the stuff is dehydrating, major contribution to headaches. Better to avoid taking additional medication, even if it's otc. / Old Hat (30 yrs with left-sided UC; presently in remission taking Colazal)

jano437
Veteran Member


Date Joined Jul 2005
Total Posts : 1614
   Posted 1/2/2010 9:44 PM (GMT -6)   
Thanks for the advice
Diagnosed July 2005 with Pancolitis
Asacol 4 tabs 3 times daily
Pro-Bio
Multivitamin


ednort
New Member


Date Joined Dec 2009
Total Posts : 10
   Posted 1/30/2010 12:07 AM (GMT -6)   
I have been on this med for about 2 months, but had med increased about 15days ago to 500mg at 2 tabs 3 x a day. This is taking along time to help my condition. Should I give up hope on this med? Anyone had similar results? How long should this med start to kick in??

Thanks

killcolitis
Veteran Member


Date Joined Dec 2009
Total Posts : 2396
   Posted 1/30/2010 12:27 AM (GMT -6)   
My daughter with UC (pancolitis) was put on pentasa following her diangnosis this summer. She then relapsed. We sought a second and third opinion from two top pediatric GIs (she's very young and her first GI was happy to let her go straight to Imuran but we were not comfortable with this and suggested sulfasalazine first after reading that it was more effective than other ASAs). The two other GIs we sought opinions from both suggested sulphasalazine as a next step. One of them told us that there was a big conference in Chicago (?) last year where they discussed findings that sulphasalazine with folic acid is more effective than other asas. It has an antimicrobal component as well as an anti inflammatory one. One of these GIs is the top pediatric guy in Italy, the other the top in Canada. Both suggested we start with a high dose and then go down later if possible. We haven't started with the drug yet though. We were told it takes up to four weeks to kick in.

jano437
Veteran Member


Date Joined Jul 2005
Total Posts : 1614
   Posted 1/30/2010 12:38 PM (GMT -6)   
ednort said...
I have been on this med for about 2 months, but had med increased about 15days ago to 500mg at 2 tabs 3 x a day. This is taking along time to help my condition. Should I give up hope on this med? Anyone had similar results? How long should this med start to kick in??

Thanks
 
 
 
 
 
My doctor told me it takes at least 3 months for it to kick in

Diagnosed July 2005 with Pancolitis
Sulfasalazine
Pro-Bio
Multivitamin

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