What times do you take Asacol?

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Regular Member

Date Joined Nov 2008
Total Posts : 360
   Posted 4/9/2010 6:08 AM (GMT -7)   
I take Asacol - 12 pills 4x day.  I take them at 6, 11, 5 and 9.  I find that in the morning, because it has been so long since I have taken a pill, I have cramping and pain.  Within 20 minutes of taking my first daily dose, the pain and cramping goes away.  I tried keeping the 9 pm pill until I visit the bathroom in the middle of the night but I don't always get up or even remember if I do.
I was interested in what times of the day everyone takes their pills and do you find you have to move up the times sometimes?
Presently on: 600 mg. Remicade every 5 weeks
                   Venofer infusion every 5 weeks
                   B12 every 5 weeks              
                   12 Asacol daily
                   Zofran as needed
Dealing with Colitis since 2003, Gastro-Paresis, Reflux, IBS and Gluten and Dairy Intolerance
"Food is in my dreams and in my nightmares!"

Veteran Member

Date Joined May 2008
Total Posts : 574
   Posted 4/9/2010 6:49 AM (GMT -7)   
Hi i take mine morning and night morning by 9.30 and night bed time but before midnght.
  Diagnosed 22.5.08 with Lft sided U/C
 Asacol 800mg x2 twice daily
 co codamol 30/500x2 when needed
 buscopan 20mg when needed
 6mp 50mg daily

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Date Joined Apr 2004
Total Posts : 23549
   Posted 4/9/2010 6:55 AM (GMT -7)   
When I was on 12 Asacol a day, I split it 4x3 because it was easier for me to remember. I have always used the 3x's a day. I'm on Colazal now and I take them at 8am, 1pm and 9:30pm.

If you are getting cramping after waking, it is probably just because your colon is "waking up". I doubt that Asacol can disperse it's med in just 20 minutes. So maybe it's just the fact that you are taking your med that your mind is unconsiously soothing your gut?
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Regular Member

Date Joined Mar 2010
Total Posts : 312
   Posted 4/9/2010 8:17 AM (GMT -7)   
I take asacol HD twice a day. 9:30am and 9:30pm
juju / UC since July 2001
Flares: Jan 2006, March 2010
Currently: Flaring since 2/25/10 :(
Meds: Prednisone 10mg/day, Asacol HD 800mg x4/day, [del]Fish Oil 3g/day[/del]

Veteran Member

Date Joined Mar 2010
Total Posts : 1180
   Posted 4/9/2010 8:26 AM (GMT -7)   
I take one Asacol HD when I wake up and after lunch. I found that I passed partly dissolved pills if I took them later in the day.
Diagnosed with proctosigmoiditis as my 50th birthday present Dec 2009
4.8 grams Asacol HD plus 1000mg canasa daily for 8 weeks
Now on 1.6 gr Asacol HD daily

UC Momma
Regular Member

Date Joined May 2009
Total Posts : 113
   Posted 4/9/2010 8:30 AM (GMT -7)   
I always take them right before a meal. Around 8am, 12:00pm, and 5:30pm. Just easier for me to remember that way.
Diagnosed in 2007 w/ left sided colitis a year after birth of first child
First major flare after diagnosis in March 2009, flare free until miscarriage in March 2010
Currently taking 9 Asacol/day, Align probiotic, prenatal vitamin

Elite Member

Date Joined May 2003
Total Posts : 29856
   Posted 4/9/2010 10:02 AM (GMT -7)   
I take mine after breakfast or brunch depending on what time I eat....between 10 and 1. and my nightly dose somewhere between 11 and 1.


Veteran Member

Date Joined Jul 2008
Total Posts : 748
   Posted 4/9/2010 11:40 AM (GMT -7)   
I only take mine twice a day, so about 8:30 am and 8:30 pm.

I also have some cramping in the mornings sometimes that tends to disperse after breakfast, but I agree with Sherry that I am not sure the Asacol would make a difference in that short a period of time.
Getting Closer to Remission!!!!
34 years old, stay at home mom of 2 girls, ages 4 and 3
Diagnosed in March 2007, symptoms started Dec. 2006
Currently on:
OUT of Humira trial-it stopped working
TAPERING pred (currently on 35mg), started remicade 2/26/10, otherwise taking Asacol (6/day), slow-fe iron, milk thistle, multivitamins, calcium, Ultimate Flora Critical Care and vitamin C but off all other supplements for the time being at the request of my GI.

Regular Member

Date Joined Jan 2010
Total Posts : 54
   Posted 4/9/2010 12:09 PM (GMT -7)   

Have you considered switching to Lialda?  I've had good results, and they can be taken once a day.  3 Asacol = 1 Lialda.

While I was flaring I would take 4 at night (with food, otherwise the high dosage would cause cramping for me).

Hope this helps!

*Female, 31 yrs old - currently in remission
*Maintaining with 2x lialda nightly & 1 rowasa enema every other night
*diagnosed with proctitis in fall '05 - remission after 1 month of Canasa suppositories
*2nd flare started in Apr '09, diagnosed with severe left-sided colitis in Jan '10
*remission as of March '10 after combining 4x lialda and 1 rowasa enema nightly for 8 weeks (started the Lialda in Nov '09 - helped, but didn't work on its own)

Veteran Member

Date Joined Aug 2009
Total Posts : 832
   Posted 4/9/2010 12:14 PM (GMT -7)   
I take 8 per day, 4 in the morning (8ish), 4 at night (8 or 9ish).  This has helped me I think to have a consistent amount of the med in my system.
*Amy, 33, dx with idiopathic colitis July 2009, confirmed UC Sept 2009

Asacol 4 pills 2 times daily (as of March 2010, started at 6, then went to 9, now cutting to 8)
Rowasa (2 nights in a row then skip a night...on the super slow taper this time!)
Probiotic: Ultimate Flora Critical Care

Regular Member

Date Joined Nov 2008
Total Posts : 360
   Posted 4/9/2010 12:28 PM (GMT -7)   
With my insurance Lialda is almost twice the cost of Asacol, so I will not change. I do find that within 20 minutes of taking Asacol, my cramping lessens. I know it sounds strange, but for the 6 years I have been on it... this is the case.

Asacol works for me pretty well. I was just interested in how everyone splits their dosage up.
Presently on: 600 mg. Remicade every 5 weeks
                   Venofer infusion every 5 weeks
                   B12 every 5 weeks              
                   12 Asacol daily
                   Zofran as needed
Dealing with Colitis since 2003, Gastro-Paresis, Reflux, IBS and Gluten and Dairy Intolerance
"Food is in my dreams and in my nightmares!"

Forum Moderator

Date Joined Dec 2008
Total Posts : 15414
   Posted 4/9/2010 12:56 PM (GMT -7)   
7:30am, 3:00pm and 11:00pm
March 2007: Diagnosed with mild proctitis - Treated with Canasa (as needed)
August 08 - December 08: Relapse & Anemic - Treated with Asacol (9/day) + Canasa 2x/day
January 09 - December 09: Remission!! Canasa nightly + Asacol (9/day) + Probiotics + Iron
December 09 - January 10: Flare :(
Current: 10mg prednisone, 9 Asacol, Canasa

Durango Kid
Regular Member

Date Joined Jul 2009
Total Posts : 330
   Posted 4/9/2010 1:00 PM (GMT -7)   
4X3 at 8am:ish, 5pm:ish and 1am:ish.
U.C. (Proctosigmoiditis) DX 2004 after quiting smoking
Currently flaring since 7/07/09 (close to remission)
CURRENT MEDS: Asacol 400mg 4x3 daily; Finally Off the evil Pred; Azathioprine 100mg (Discontinued due to elevated liver enzymes); Hydrocortisone enema every other night(tapering); Probiotic 20 billion cfu; Psillium husk powder; Fish oil; Multi-vitamin
I don't believe diet contributes to my flares, however some foods tend to irritate symptoms while flaring.

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