I split my 2.5mg in half and after I do a week at 1.25mg, I will do 1.25 every other day.
Seems a little neurotic but that's what my doctor said to do and I trust her, I've had better luck when I listen to her. Maybe you should drop the dose very slowly...
March 2007: Diagnosed with mild proctitis - Treated with Canasa (as needed)
August 08 - December 08: Relapse & Anemic - Treated with Asacol (9/day) + Canasa 2x/day
January 09 - December 09: Remission!! Canasa nightly + Asacol (9/day) + Probiotics + Iron
December 09 - January 10: Flare :( - 40mg prednisone + Canasa - Relapse @ 2.5mg - Began Slower Taper
Current: prednisone, Colazal, Canasa