I have been flaring for about 5-6 years. I too am on Colozal (9 pills). I also take Rowassa and VSL #3 (sometimes).
I used to be on Asacol but out of the blue it stopped working. My doc wanted to put me on it and I said no, I want to try the other 5asa meds. I suggested Colozal because with Asacol I was passing the whole pill and Colozal breaks up faster. He said I could give it a try. Well after my last colonoscopy this past month he said that I am in a major flare and he was surpised I haven't been calling him sooner. He said I adjusted my life so much to my condition and symptons to a fault. I make about 10 - 15 pitstops a day, I have pain, I am careful where I go in regards to bathroom situations (need to know how many stalls there are...knowing where the bathroom is, is not enough), throwing up atleast 1 a week. But I do it and then go on my daily business.
He said that I started to get a few polyps b/c of the flare. Since we have UC we have a better chance of getting colon cancer regardless of how often we get checked.
So that was a wake up call to me. Sucking it up and dealing with the pain is actually bad. He wanted me to go on Predisone until the Remicade kicked in. I refused it. Since he really didn't want to put me on it before because of the side effects. I told him I can deal with my issues a few more months.
So in a nutshell I decided to go on remicade because "dealing" with my symptons was doing much more harm.
Remicade works faster than 6mp. Both have scary side effects, but if one works faster then I would want to go with that one. Also I have found more people who have better success and less side effects with remicade than with 6mp. My sample size isn't that large for this. Its just hte people who I have talked to.
I have left sided moderate UC.
I have had UC since I was 19.