Salofalk versus asacol...what has been your experience with it

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katkat
Regular Member


Date Joined Feb 2005
Total Posts : 237
   Posted 3/5/2011 11:03 AM (GMT -7)   
Had GE appt Mar 3.11. It was a good short meeting. GE is young, open to other alternatives when I feel ready to. Referral to him was recommendation for a resection of colon. But since doing fine since last scope in April 2010, he says will not go with recommendation. And to get a colectomy out of my head, he says not any time soon. So relieved! But of course, may happen pending toxic megacolon or any signs of dysplasia. So I am good with that. I think we all understand the possibilities of this disease!

He felt I should increase asacol though but I mentioned that anything higher than 10 pills makes my kidneys hurt and I get the chills also. So he is recommending a switch to salofalk, that it is pretty much the same as asacol but the coating ingredients a bit different, as it is probably the coating ingredients that I get the reaction to.

So I'm asking you guys what you experience has been with this! Right now I'm doing about total 5 to 6 pills per day, 3inam 3inpm and it seems to be OK to tolerate so far.

I didn't get a chance to ask about the putting on weight question though. I see him in May 2011 for a scope. I figured to let him have a look there since he is a GE! Depending on how things are he said he usually has UCer's get a scope either every year or every 18 months.

Tell you more later....
46 y/old female OntCanada Current: UC trying to sneak up again. Fighting back. Asacol 400mg 7/day=4am,3pm Entocort(budesonide enema 2.3mg) 1xnite as req'd. No prednisone. Floravit yeast/gluten free liquid iron 10 ml 2x/day. Prairie Naturals multi vit 1/day. Carlson Vit D3, 2000 IU, 1 pill every 4 days. Finished 7 day 500 mg. flagyll Feb 20.11 for BV.

quincy
Elite Member


Date Joined May 2003
Total Posts : 29860
   Posted 3/5/2011 11:48 AM (GMT -7)   
Sounds like a good appointment and good news for you at this point.

What did he say regarding the enema? Can you not take the 5ASA enemas?

Kristie takes the Salofalk pills...don't know if she used the Asacol, however.

I would think that he would have considered something else such as Pentasa...

The Salofalk pills are 500 mg compared to the 400mg of the Asacol. Maybe your gut will have the right PH to have them work better for you.

q
*Heather* I give suggestions, do with them what you will.
Status: ...Asacol 3 @ 2x daily; Salofalk enema @ 3rd night (nightly/ flares, tapered/maintenance)
~diagnosed January 1989 UC (proctosigmoiditis)
~Bentylol 20mg as needed; Zantac 150mg; Pulmicort/Airomir (asthma);Effexor XR 37.5 (depression)
~vitamins/minerals/supplements; Probiotics....(RenewLife Ultimate Flora Critical Care+Primadophilus Reuteri capsules @ bedtime)
~Metamucil capsules 6 twice daily with meals; Vitamin D 4500 IU
~URSO for PBC(or PSC?) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS" worth it !!!

JamesonM
Regular Member


Date Joined Jan 2011
Total Posts : 63
   Posted 3/5/2011 12:02 PM (GMT -7)   
I have been taking 2g/bidaily salofalk for quite some time, however I have just recently switched to imuran because the 5-asa doesn't seem to be working anymore. When I was first prescribed salofalk it worked quite well, hope you have a good experience with it. I never experienced any side effects that I can remember using this drug.
24 year old male, UC since 2005, Salofalk 2g/bidaily, 75mg effexor

quincy
Elite Member


Date Joined May 2003
Total Posts : 29860
   Posted 3/5/2011 12:04 PM (GMT -7)   
jameson...no rectal meds at all? could be the reason that the salofalk pills weren't working...
OR if you were just using the enemas without the pills...again, same possibility.

q
*Heather* I give suggestions, do with them what you will.
Status: ...Asacol 3 @ 2x daily; Salofalk enema @ 3rd night (nightly/ flares, tapered/maintenance)
~diagnosed January 1989 UC (proctosigmoiditis)
~Bentylol 20mg as needed; Zantac 150mg; Pulmicort/Airomir (asthma);Effexor XR 37.5 (depression)
~vitamins/minerals/supplements; Probiotics....(RenewLife Ultimate Flora Critical Care+Primadophilus Reuteri capsules @ bedtime)
~Metamucil capsules 6 twice daily with meals; Vitamin D 4500 IU
~URSO for PBC(or PSC?) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS" worth it !!!

JamesonM
Regular Member


Date Joined Jan 2011
Total Posts : 63
   Posted 3/5/2011 12:08 PM (GMT -7)   
Yeah I mentioned that to my GE on Thursday when I had my appointment, she said since my UC affects my entire colon, it would only be treating a small area, and she didn't feel as thought it would be effective... I asked her if I had done everything "properly" up to this point, and she said yes and that the next step was imuran... what are your thoughts on this? I held of trying imuran for a few months to try and get things to settle down on their own without any success, prednisone seemed to be the only med which held any real benefits, but I don't want to rely on such a nasty drug all the time. Seems as though every 3-6 months I would have a nasty flare up, usually requiring hospitalization.
24 year old male, UC since 2005, Salofalk 2g/bidaily, 75mg effexor

quincy
Elite Member


Date Joined May 2003
Total Posts : 29860
   Posted 3/5/2011 12:23 PM (GMT -7)   
As you see from my signature, the both ends approach regardless of how much is involved makes total sense regarding oral/rectal topical meds such as 5ASA or the steroids.

Pills to cover above the sigmoid and the sigmoid, retention enemas to cover the rectum and sigmoid.

I've done it for 22 years. Now, my entire colon is NOT affected...but who is to totally say that if I didn't use my meds effectively that it wouldn't have been?

I would totally do the oral/rectal route long before going on the immunosuppressives, and NO, no, no...you didn't do all that could be done YET.

If you exhausted all the oral 5ASA meds...and using the rectal...then OK...next step please.

Are you also using probiotics and fibre supplements?

Oh, and I just saw my GI on Thursday as well and we discussed the rectal..and he said...if I could only convince other patients to be as compliant with the rectal meds...lol. He was surprised at my statement of how many GIs seem to discourage the use of rectal meds.

Rectum RULES!!!! it's the first to become inflamed and the last to heal.

Common sense regarding that aspect...
q
*Heather* I give suggestions, do with them what you will.
Status: ...Asacol 3 @ 2x daily; Salofalk enema @ 3rd night (nightly/ flares, tapered/maintenance)
~diagnosed January 1989 UC (proctosigmoiditis)
~Bentylol 20mg as needed; Zantac 150mg; Pulmicort/Airomir (asthma);Effexor XR 37.5 (depression)
~vitamins/minerals/supplements; Probiotics....(RenewLife Ultimate Flora Critical Care+Primadophilus Reuteri capsules @ bedtime)
~Metamucil capsules 6 twice daily with meals; Vitamin D 4500 IU
~URSO for PBC(or PSC?) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS" worth it !!!

katkat
Regular Member


Date Joined Feb 2005
Total Posts : 237
   Posted 3/5/2011 6:45 PM (GMT -7)   
Yes, we did talk about the enemas, he said he is glad that I use them and they are helping me. He commented on my 3 page list and said wow, you are an organized patient and if he could keep it. I said yes, one copy is yours, this was to make things easier because he must see so many other patients and that I did it so I wouldn't forget certain topics as well.

Since I've had two major flares and a couple of minor ones, he said he wasn't too concerned at the moment because the asacol and enemas are helping. He said he has seen other patients that are having a harder time. He actually sounded a bit surprised that I've only used asacol only and only recently the enemas since 2004 and that I didn't use much steroids also. I said, yes, I hope that I don't need to but understand that if I do require I will use the steroids.

We also talked about if/when the surgery scenario ever comes into play, what would I prefer. I said the permanent ileostomy for sure, just to avoid any problems with j-pouches, etc., as things are different for other people. With my luck, I would probably have major problems. (I'm such a pessimist some times, drives me crazy!)

He saw the 6 pills per day though and felt I should be up a bit higher, hence the salofalk med change.

I'm still waiting for a gallbladder removal surgery date and getting skinnier! It's really p'ing me off! I can only eat certain foods and drinks. I miss milk and cheese and steak and butter and on and on the list goes. It's getting to almost be anything I eat makes the gallbladder have short bursts of pain!

UC is holding out OK, no blood or diarrhea since January 18, 2011 (stupid antibiotics!) they put you in a situation d*** if you do and d*** if you don't!

Q: We didn't talk about changing the enemas though as that did not cross my mind. Do you think that would make difference? I am sort of hesitant about changing the pills too but because of the increase of asacol at times, the reaction is not what I want. I see in your signature that you use the salofalk enema. As for the pentasa I'll have to research about that. I've never really read about it yet.

Oh yes, I almost forgot, I'm not on any vitamins at the moment because of a possible surgery (either emergency or booked). They want you to be off them for at least 10 days prior to. And haven't been smoking also because of this possibility also. So I am hanging on! Once I've recovered from the surgery my plan is to use quincy's meds/vitamins/fibre methods to maintain this d*** UC. Q, it sounds like this has successfully worked for you so far, so it won't hurt to try!

Later.....
46 y/old female OntCanada Current: UC trying to sneak up again. Fighting back. Asacol 400mg 7/day=4am,3pm Entocort(budesonide enema 2.3mg) 1xnite as req'd. No prednisone. Floravit yeast/gluten free liquid iron 10 ml 2x/day. Prairie Naturals multi vit 1/day. Carlson Vit D3, 2000 IU, 1 pill every 4 days. Finished 7 day 500 mg. flagyll Feb 20.11 for BV.

quincy
Elite Member


Date Joined May 2003
Total Posts : 29860
   Posted 3/6/2011 12:35 AM (GMT -7)   
So I take it you liked Dr. Moffat? Was he in the St. B hospital?

I think the Salofalk oral is worth the try...how many would you be using? Same amount of pills?" just a higher dosag amount bit a bit..?

If you haven't used the Salofalk enemas, I would think that would be a better way to go...unless you are sensitive to them.

It's awesome NO pred.

The surgery is to totally have the gallbladder removed? Will you be in Winnipeg to have that done?

I had my doctors' appointments on Thursday too...all is fine. Did you stay in the city long?

q
*Heather* I give suggestions, do with them what you will.
Status: ...Asacol 3 @ 2x daily; Salofalk enema @ 3rd night (nightly/ flares, tapered/maintenance)
~diagnosed January 1989 UC (proctosigmoiditis)
~Bentylol 20mg as needed; Zantac 150mg; Pulmicort/Airomir (asthma);Effexor XR 37.5 (depression)
~vitamins/minerals/supplements; Probiotics....(RenewLife Ultimate Flora Critical Care+Primadophilus Reuteri capsules @ bedtime)
~Metamucil capsules 6 twice daily with meals; Vitamin D 4500 IU
~URSO for PBC(or PSC?) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS" worth it !!!

katkat
Regular Member


Date Joined Feb 2005
Total Posts : 237
   Posted 3/6/2011 7:29 PM (GMT -7)   
Yes, I actually like him, I was very surprised to see that he was young, I was expecting a stodgy elderly doctor. It was the St. Boniface hospital. I hear that this is the better one to go to. I've never been there before, so I hope it is. Never been one to go to hospitals unless absolutely necessary.

He did say the salofalk is 500 mg and we didn't talk details about how much. Although I know we should take what the doctors prescribe, I usually go with less. For sure I went with less with asacol because of the reaction and that when not in a flare, they would make me so constipated. I know if a flare comes up, it would take a while for the medication to kick in if I had to increase it but what the heck, I'll have to work on it when a flare comes up again.

Yes, no prednisone since 2004 and hope (knock on wood) that I don't require it soon enough! That was one tough go last time. Again, I forgot to ask him, it was on my list, why they start out on prednisone at 40 mg/day right off the hop?! That stuff through me for a four week doozy before the shorter taper, I thought I would lose my mind!

I've asked if I can get the surgery done in Winnipeg, as the small town I'm in, doesn't have me scheduled yet! I hope the city can do it quicker and better? I heard some scary stories about some people getting sent to Winnipeg for ERCP because of stone lodged in the bile duct or pancreas either shortly after surgery or 2 weeks after! I understand that it happens though. Yikes...It's going to be 3 months on March 18th with the gallbladder off/on pain and eating bland foods and drinking lots of water. I'm going to weigh 115lbs soon! I don't like that. Oh yeah, I asked for blood work as well to establish a base line for this visit. This is only a second visit I've had with a GE, the other was in 2004 in Vancouver.

No, didn't stay long in the city, left about 3 p.m. just enough time for a quick visit to the casino and lunch. It's nice to get away for a quick jaunt now and then.

Glad to hear your appointment went well. It always feel such a relief, isn't it? You are definitely doing something right there, Quincy! And I hope to be following your methods soon after the gallbladder surgery!
46 y/old female OntCanada Current: UC trying to sneak up again. Fighting back. Asacol 400mg 7/day=4am,3pm Entocort(budesonide enema 2.3mg) 1xnite as req'd. No prednisone. Floravit yeast/gluten free liquid iron 10 ml 2x/day. Prairie Naturals multi vit 1/day. Carlson Vit D3, 2000 IU, 1 pill every 4 days. Finished 7 day 500 mg. flagyll Feb 20.11 for BV.

C_G_K
Veteran Member


Date Joined Dec 2006
Total Posts : 914
   Posted 3/6/2011 9:14 PM (GMT -7)   
Asacol has never been as effective for me as Salofalk. Since I live in the U.S. now, and Salofalk is unavailable here, I have tried several times to switch from Salofalk tabs to Asacol. Every single time I've tried, my symptoms have gotten worse. I've just given up trying to switch over, and order Salofalk from Canada, despite the high cost. The Salofalk costs me about $2500/year out of pocket, but I don't have a lot of choice. I've tried Apriso thinking it would be similar to Salofalk, but it wasn't as effective, same with Pentasa. I've never tried Colazal or sulfasalazine so I don't know if they would work for me.

In my opinion, based on my experience, asacol and Salofalk are not equivalent. (My profile needs to be updated as I am back to taking Salofalk instead of Asacol).
DX Pancolitis 2003. Subsequent flares limited to left side
Flare every 2-3 years.
Asacol 12 tabs daily,
Probiotics: Primal defense, Ultimate Flora and VSL#3DS. Fiber: Psyllium and "super seed".
Allergic to Imuran

Current flare last 9 months.. No diarrhea.
Switched from Cortifoam to Colocort 2x daily.
Flared again while tapering. Inflamed up to about 12"

Post Edited (C_G_K) : 3/6/2011 9:19:08 PM (GMT-7)


quincy
Elite Member


Date Joined May 2003
Total Posts : 29860
   Posted 3/7/2011 1:08 AM (GMT -7)   
katkat...Yes, St. B has a gastro clinic. It's a teaching hospital and I believe some research.

I don't know about needing an ercp, but you would if there are stones stuck in the pancreas or bile ducts. Hope they get them all and that you're not like my sister and make them all on her own without a gallbladder..lol.

If you get it done in the city...I would love to visit you :-)

Hope you don't have too many bad gallbladder pain days!

Keep us posted.
q
*Heather* I give suggestions, do with them what you will.
Status: ...Asacol 3 @ 2x daily; Salofalk enema @ 3rd night (nightly/ flares, tapered/maintenance)
~diagnosed January 1989 UC (proctosigmoiditis)
~Bentylol 20mg as needed; Zantac 150mg; Pulmicort/Airomir (asthma);Effexor XR 37.5 (depression)
~vitamins/minerals/supplements; Probiotics....(RenewLife Ultimate Flora Critical Care+Primadophilus Reuteri capsules @ bedtime)
~Metamucil capsules 6 twice daily with meals; Vitamin D 4500 IU
~URSO for PBC(or PSC?) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS" worth it !!!

katkat
Regular Member


Date Joined Feb 2005
Total Posts : 237
   Posted 3/18/2011 9:44 PM (GMT -7)   
To GGK, and Kristie
If I can ask, why did you change from/to asacol salofalk? Did you have side effects? The only reason for my change was anything over 8 pills/day with asacol would give me the chills and start affecting my kidneys with mild pain. GE said, salofalk is pretty much the same as asacol just a different coating that shouldn't give me those side effects. Otherwise, I was doing great on asacol between 6 to 8 pills.

To Q, my surgery will be done in my town here, finally have a surgery date, April 19th. I was so hoping Winnipeg too. Yes, would loved to have visit me!
But I will be in city May 18 - 20, scope on 19th, then a follow-up in September. I'm still aspiring to maintain my UC with your meds routine after my surgery! If you can do it, so can we! Enemas rule! LOL (I'm finding it does really help!) but I am experiencing some lower left side pain now, usually at the end of the work day. strange....it was starting after my GE visit...stress?...tired?...I don't know
46 y/old female OntCanada Current: UC trying to sneak up again. Asacol 400mg 7/day=4am,3pm Entocort(budesonide enema 2.3mg) 1xnite as req'd. No prednisone. No vitamins or probiotics or fibre supplements yet. Waiting for gallbladder surgery, require 10 days non-usage of these before surgery.
antibiotcs Jan 14 to 18.11, Feb 14 to 21.11, flare on hold since.

quincy
Elite Member


Date Joined May 2003
Total Posts : 29860
   Posted 3/18/2011 11:20 PM (GMT -7)   
LOL...yeah, the enemas rule! it's good you're having success with the Entocort. Is it a liquid or foam?

Nice you won't have to travel for the surgery and will be close to home. Easier to travel for c-scopes. So, Dr. Moffat will be doing the c-scope?

Curious what purge you'll be doing for the scope?

Do you have any antispasmodics? That might help the lower left pain..I suspect that it might be spasming. especially if your bms are formed. That area has to work a bit harder when it's got stool to move through...

If we can't get together before the scope, maybe we can do it in Sept during your follow-up.

Happy to hear things are doing a bit better.
q
*Heather* I give suggestions, do with them what you will.
Status: ...Asacol 3 @ 2x daily; Salofalk enema @ 3rd night (nightly/ flares, tapered/maintenance)
~diagnosed January 1989 UC (proctosigmoiditis)
~Bentylol 20mg as needed; Zantac 150mg; Pulmicort/Airomir (asthma);Effexor XR 37.5 (depression)
~vitamins/minerals/supplements; Probiotics....(RenewLife Ultimate Flora Critical Care+Primadophilus Reuteri capsules @ bedtime)
~Metamucil capsules 6 twice daily with meals; Vitamin D 4500 IU
~URSO for PBC(or PSC?) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS" worth it !!!

katkat
Regular Member


Date Joined Feb 2005
Total Posts : 237
   Posted 3/19/2011 11:38 AM (GMT -7)   
The prep will be golytely. I had that before, it wasn't that bad really. I think it's a bit better than the acidic pico salax.

Yes, Dr. Moffat will be doing the scope and said he wants to take a lot of samples. Yikes...I figured he's the GE, should have a better idea of what's going on. Surgeons only wants to slice and dice.

I'll have to drive in the day before the scope, will stay at a hotel and then scope then back to hotel again. I want to stay close, just in case. The last scope, I had a hard time after from the anaesthetic, didn't go to hospital though. Just rode it out, dry heaving was going on. Yuck.

Almost forgot, enema is liquid, have to drop a pill into, then shake it. Yes, I'm happy no blood or diarrhea. It's such a relief to be almost normal for a while.

I'll probably be in city late p.m, before starting golytely if you want to get together or wait until September. Either way, let me know.
46 y/old female OntCanada Current: UC trying to sneak up again. Asacol 400mg 7/day=4am,3pm Entocort(budesonide enema 2.3mg) 1xnite as req'd. No prednisone. No vitamins or probiotics or fibre supplements yet. Waiting for gallbladder surgery, require 10 days non-usage of these before surgery.
antibiotcs Jan 14 to 18.11, Feb 14 to 21.11, flare on hold since.

quincy
Elite Member


Date Joined May 2003
Total Posts : 29860
   Posted 3/19/2011 12:17 PM (GMT -7)   
That would be great....I'll contact Sherry regarding email to see if the May get together can work.

The Golytely ...sucks to do the gallon...but a sure clean-out! Bring a straw! At least you can eat that morning...no starving for days before. What time do you usually start it...5ish?

The enema...a pill in liquid? is that how it comes, or did the doc suggest you do it that way? wow, obviously I'm not so up on the enemas as I may believe..lol.

Kristi comes and goes...I'm assume she's doing well so isn't here often. Have you changed to the Salofalk yet?

q
*Heather* I give suggestions, do with them what you will.
Status: ...Asacol 3 @ 2x daily; Salofalk enema @ 3rd night (nightly/ flares, tapered/maintenance)
~diagnosed January 1989 UC (proctosigmoiditis)
~Bentylol 20mg as needed; Zantac 150mg; Pulmicort/Airomir (asthma);Effexor XR 37.5 (depression)
~vitamins/minerals/supplements; Probiotics....(RenewLife Ultimate Flora Critical Care+Primadophilus Reuteri capsules @ bedtime)
~Metamucil capsules 6 twice daily with meals; Vitamin D 4500 IU
~URSO for PBC(or PSC?) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS" worth it !!!

katkat
Regular Member


Date Joined Feb 2005
Total Posts : 237
   Posted 3/19/2011 7:12 PM (GMT -7)   
Sounds good for May! Barring any complications from the April 19th surgery. Yes, 2 litres prep start around 6pm it says, then other 2 litres 4 hrs prior to procedure. Procedure at 1:00 pm. Oh what memories! lol

The enemas are called glucorticosteroid enema, (entocort) 2.3 mg comes prepared in individual containers (or called vehicle) gotta like that fancy name, then there's a pill which is the dispersible tablet for preparation of budesonide enema you put into it, shake it well, then it's ready to go.

It's contents are 115 mL but they're doing good for me so far. Can't complain. After a while, it all comes done to a routine doesn't it? We gotta do, what we gotta do! It comes in a box for 7 nights, vehicles, tablets and a handy little box with plastic baggies to keep your hands clean. Its quite efficient on its own packaging.

Forgot to mention, also experiencing some mild pelvic pain as well, since Feb 20th off and on. I'm hoping it's just related to the gallstone pain. Not sure, but I'm going to get that checked out too.

I think I'm slowly falling apart sometimes! Just sucks....

Yes, I started the salofalk today is day 2. First day, was a bit of stomach pain, like when taking the hpac for the hyplori, then it went away later in the pm. Feeling a bit dizzy now and then but otherwise no major problems (knock on wood) in the bm department.

OK with email.
46 y/old female OntCanada Current: UC trying to sneak up again. Asacol 400mg 7/day=4am,3pm Entocort(budesonide enema 2.3mg) 1xnite as req'd. No prednisone. No vitamins or probiotics or fibre supplements yet. Waiting for gallbladder surgery, require 10 days non-usage of these before surgery.
antibiotcs Jan 14 to 18.11, Feb 14 to 21.11, flare on hold since.

quincy
Elite Member


Date Joined May 2003
Total Posts : 29860
   Posted 3/20/2011 12:36 AM (GMT -7)   
Sounds like a good plan regarding meeting in May...

Oh...split dosage. Never did that before, but should be OK.
I've never had a late scope..always 8 or 9ish.

Hope the pelvic pain is related to something rather than nothing...again..can't suggest the antispasmodics enough..it might just take the edge off especially till your scope.

Ah, never realised there was mixing involved with the enemas. Now, that's dedication!!

Your dizziness....are you thinking it's from the salofalk? Did you just drop the asacol and then start the salofalk?

Do you take them on an empty stomach? They don't dissolve there...hope it's not anything else going on.

Good to hear the bm department is better.

Hope tomorrow is a better day...
q
*Heather* I give suggestions, do with them what you will.
Status: ...Asacol 3 @ 2x daily; Salofalk enema @ 3rd night (nightly/ flares, tapered/maintenance)
~diagnosed January 1989 UC (proctosigmoiditis)
~Bentylol 20mg as needed; Zantac 150mg; Pulmicort/Airomir (asthma);Effexor XR 37.5 (depression)
~vitamins/minerals/supplements; Probiotics....(RenewLife Ultimate Flora Critical Care+Primadophilus Reuteri capsules @ bedtime)
~Metamucil capsules 6 twice daily with meals; Vitamin D 4500 IU
~URSO for PBC(or PSC?) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS" worth it !!!
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