The Journal of Gastro article was very interesting. Thanks for the link; great stuff on this site. On the whole the report is encouraging too. I am going to print it out and discuss it with my GI. At a minimum, I wonder if I can get one of these titers for the bacteria antibodies they tested. If I got the antibodies, I might want to push for the therapy. BUT, as I read, it is a very unpleasant two weeks, with a lot of discomfort, sickness, and flare-like symptoms - so I would want to choose the time carefully.
@C_G_K: what drugs/dosages/durations did you get exactly? Was it the same amounts/durations reported in the article, or some variation? Just curious. Also, I don't mean to pry, but can you say something more about how you got the concurrent prescriptions for 3 specific antibiotics? I can see the doc forgetting a prescription for one - especially if there was some other reason for an antibiotic. But my mind just shuts down at the thought of having someone prescribe 3 concurrently - which is very unusual/memorable, and them having them forget it. Something is missing here. Don't want to pry, but since so many folks seem ready to lynch your doc, or condemn prescription medicines (seemingly forgetting that antibiotics are also prescription meds), or to make broad generalizations/assertions that docs are cretins that don't give a damm about patients - well given the responses of some posted here, I just really wonder about the circumstances of the antibiotic prescriptions. No insult intended. Just trying to make sense of things.
@everyone: The article is encouraging, but lets not lose sight of the fact that the study has not been replicated yet, that over 50% of the people treated with antibiotics got absolutely no benefit, that over half of the people treated had unpleasant side effects, and two had some sort of pronounced "adverse event". Prior studies with single antibiotics (some of them) had shown short-term improvement, but no long term improvement or remission about a year later. Likely why some docs may have voiced the opinion that UC would come back. This study did find long term benefit -EXCITING NEWS - but as I read it, 19 treated patients versus 16 placebo patients had remission at 12 months. While statistically significant in this dataset, this was only a difference of 3 people. We may not want to demand that established medical protocols be immediately reworked without further research. ... and lets not forget that OVER HALF of the people given the 3 antibiotics showed no clinical improvement.
... always glad to read of anybody's remission
... definitely encourage folks to find/change GI docs if open discussion and patient involvement in choices is not happening
... not so happy to see folks piling on against meds and docs generally, but I empathize with the pain and frustrations that accompany both UC and/or just having to navigate todays' medical care system
... interested in knowing more about the triple therapy - but clearly see that is is not a cure-all or game-changer. At least not yet a game-changer. One can hope.