I agree with fruitgirl, but it all comes down to the individual. That said, prednisone's bad points far, far outweigh any negatives of mesalamine (unless you have your own reaction to it) which you can stay on for years and years, as opposed to prednisone.
Anyway, Apriso is technically only indicated for maintenance, not inducing remission, so that's something to consider. I'm on 2x the amount because I was using it to get out of a flare (so some doctors believe it can induce remission though it's not approved for that), on top of other mesalamines and steroids.
23 y/o graduate student
Misdiagnosed with Crohn's June 2007, Diagnosed with left-sided UC and IBS August 2010
Currently: Apriso (3g), Canasa, VSL #3, Culturelle, Folic Acid, Vitamin D, B12 injections monthly
Previously: Prednisone (most recently Summer 2011), Cortenemas, Proctofoam, Lialda, Imuran (Allergic), Asacol, Remicade, Humira, Celexa (Post-Pred Depression)