I originally went on the pred at 40 mgs to get symptoms under control while I tried Imuran (since it takes a couple months for Imuran to really kick in). I went on both of them right around the same time. Within three weeks of starting Imuran, I found out that I could not tolerate the drug (described in my post "Trouble With Imuran"), and I immediately went off of Imuran and made an appointment to get on the Remicade. Since I went on Imuran and pred at the same time just over a month ago, I am still on my original pred taper from then.
My doctor told me I was prednisone dependent when my symptoms came back after I tapered off of my first round of pred. I told her I wanted to try it again, this time with less stress in my life (career change) and fewer triggers (staying away from chocolate, alcohol, etc during the taper), and she said the same thing would probably happen again, but she complied with my request. Well, she was right - it took a little longer the second time, but my symptoms came back again after I tapered off of my second round of pred, even with my high maintenance doses of asacol and mesalamine enemas. Basically it means I can't get off prednisone without my symptoms coming back, which is why she felt it necessary to bump me up to long-term immunosuppressants. (You can read all about
the pred stuff on my post called "The Dread of Pred".)
Once I finish tapering off of the pred this time, I should be just on the Remicade, Asacol HD, and mesalamine enemas. If my symptoms stay under control after I go off the pred, then I will drop the enemas and just remain on Asacol and Remicade for maintenance.
Follow my story: ronnielee-fightingforit.blogspot.com
32-year-old single female (teacher)
Dx mild/moderate ulcerative colitis 1995
Dx severe ulcerative pancolitis 2011
Imuran (tapering on), Prednisone (40mgs), Asacol HD (4800mgs), Mesalamine Enema, MMJ