Please tell me Suprep is easier than Miralax/Gatorade Prep!

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Veteran Member

Date Joined Jul 2010
Total Posts : 964
   Posted 7/20/2012 7:44 AM (GMT -6)   
I'm having a colonoscopy the first week of August. I'm on the 3 year plan b/c of polyps. I've already had 2 flex sigs in the last year for bleeding. Fun times!

Last time I did the colonoscopy prep I did the miralax/gatorade mix. I made it about 2 cups before I started throwing up. This time they gave me suprep. My colonoscopy is early (7:30am) so I will do the entire thing the night before.

Anyway just looking for any tips or encouragement! I don't mind the pooping but the nausea and puking I can do w/out!
150mg Azathioprine, Zegerid, Bentyl as needed, 10mg Lexapro
Started Humira 8/29/11; Stopped Humira 11/10/11
*Flex Sig on 6/16/11 showed moderate proctitis inflammation
**2nd flex sig on 11/7/11 got me 4 days in the hospital
Started Remicade 11/29

Elite Member

Date Joined Apr 2004
Total Posts : 23551
   Posted 7/20/2012 8:22 AM (GMT -6)   
You won't like what I have to say about Suprep. It was horrible (at least for me)! Sure you have less to drink and if you don't mind the taste of fruity cough syrup, than it might not be so bad. I couldn't finish the second bottle. I normally do not gag on the preps but this one definitely did.

I know that's probably not what you want to hear, I'm sorry. But who knows? Maybe this one won't be so bad for you!
Moderator-Allergies/Asthma and Alzheimer's, Co-moderator-UC
Diagnosed Left sided UC in '92 - meds: 6mp, Colazal, Remicade and Bentyl*Unable to tolerate ALL mesalamines*, in '11 diagnosed with IBS, Diverticulosis, Fibromylagia..I also have Sacroiilitis, Scoliosis, Raynauds, OA, PA, Rosacea, Psoriasis, Dry Eye and allergies controlled by Zyrtec and Singular

Regular Member

Date Joined May 2012
Total Posts : 226
   Posted 7/20/2012 6:05 PM (GMT -6)   
I have major problems with nausea and vomiting with the prep too. The nurse told me to make sure the mix is very cold and to use a straw. Once the nausea starts, I try to do little sips and to rinse my mouth out with water. I can usually consume 1/3-1/2 of the mix before the nausea is overwhelming. My dr told me that since it is a "diagnostic" colonoscopy the colon doesn't need to be perfect and that I should just do my best.

I hypothesize that one of the many reasons for the nausea is the sugar in the gatorade. Maybe you can find another electrolyte drink that isn't so sweet if you ever have to do the Miralax prep again?

You could also try fasting a bit longer- 36 hours instead of 24 hours made it easier for me to clean everything out last time.
Left-sided UC diagnosed October 2009.

Current meds: Imuran, Remicade, Canasa taper, Wellbutrin, flax/fish oil, multivitamin

Failed meds: Asacol, Rowasa

Bacon Girl
Veteran Member

Date Joined May 2011
Total Posts : 5490
   Posted 7/20/2012 6:39 PM (GMT -6)   
u can do what i do and just do a juice fast for a few days prior to your colonoscopy. if i feel like i haven't gotten everything out, i'll do an enema the night before the test or in the morning before i go. this has always worked for me.

i've had the same prep for all 7 of my colonscopies- NulyTely. it's that huge gallon jug that's impossible to get down. the first few times, i drank the whole thing because i didn't know any better, but now i don't put myself through the torture.
Joanna, 22
8 fecal transplants- got worse.
taking- probiotics, vit d, 4.5 mg LDN , l-carnitine, CoQ10, B6, welchol
tried- canasa, pred, 6mp, remicade, rowasa, lialda, entocort, l-glut, vit E enema, VSL enema, aloe vera, NAG, prilosec, zofran, psyllium, bentyl, cipro, flagyl
no meat, dairy, eggs, gluten. include-juices, fruits, veggies, greens, grains, soy, nuts/seeds

Regular Member

Date Joined Sep 2011
Total Posts : 499
   Posted 7/20/2012 7:21 PM (GMT -6)   
Suprep is awful! My one and only colonoscopy so far required Suprep. Made it through the first round, but the second bottle...well, lets just say I told the good Lord that if it was going to get in me He was going to have to do it! I think I drank less than 1/3 of the bottle then just quit. No point in swallowing something just to throw it up seconds later.

By the time I got to the center for the procedure, all I wanted was to be put to sleep. Told the nurse that she didn't have to explain anything to me-just knock me out and do whatever!

There really should be a better/easier way to prep for a colonoscopy.
DX: May 2011
Current meds: Imuran 150 mg
Prednisone 40mg (aaarrgh!)
Slippery Elm- 1 tsp 2 times daily
Never had rectal meds.
And this too shall pass!

New Member

Date Joined May 2014
Total Posts : 1
   Posted 5/21/2014 4:59 PM (GMT -6)   
I had a colonoscopy a few days ago and used Suprep for the first time. Mixed a bit of lemonade in addition to the water required to get the initial 16 oz. Kinda crummy smell and taste but I drank it down in three chugs, taking maybe 1 - 2 min. total. Hardest part was drinking the two additional 16 oz glasses of water afterward. I felt like a water balloon.
In about an hour it started to work, and was very effective. I started prep at 6PM evening before my procedure and was in bed and sleeping by 9:30 or so. Woke up twice to pee and only once had a bit extra clean-out material. Second dose next morning resulted in very clean bowel.
Best advantage of Suprep is lack of cramping like I've had in the past with Fleet enema prep.

Regular Member

Date Joined Sep 2013
Total Posts : 358
   Posted 5/21/2014 5:24 PM (GMT -6)   
I feel like I've done every different prep under the sun - Fleet, HalfLytely, Magnesium Citrate and most recently Suprep. One of my biggest issues with the preps are nausea. Of them all, I thought Suprep was by far the best of the worst. My doctor gave me that one because I wouldn't need to drink much less chance of nausea. For me it tasted the best of all of them. Yes, it does taste like grape cough medicine, but that didn't bother me compared to the other slimey, salty preps. It works fast and no cramping. I was pretty cleared out after the first bottle. The only bummer is waking up to take the second bottle. I like taking the preps in one shot and being done. This is not like that since it's a split dose prep. By the time I got to the second bottle I was so spent that I could only manage to get down half of it. However, I was cleaned out anyway by that time.

One thing to be aware of, because you are drinking less prep, make sure you drink plenty of fluids. It is easier to dehydrate on a prep like this versus one like HalfLytely where you mix the prep with 64 oz. of water.
-2005 dx proctitis, 2006 dx pancolitis, pathology reports on occasion have suggested crohn's colitis, 2007 10 day hospitalization due to UC

-Current Meds: Colazal 6750 mg/day, Canasa 1000mg/day, Lexapro 10mg/day

-Past Meds during flares: Lialda, Asacol, Prednisone, 6-MP, Cortifoam, Levaquin, Omeprazole, Bentyl, Cipro, methylprednisolone, protonix

-Additional Supplements: probiotics

Regular Member

Date Joined Dec 2012
Total Posts : 336
   Posted 5/21/2014 9:46 PM (GMT -6)   
I loved Suprep! It was the best for me due to it's size and I only needed to drink one bottle to get a clearish yellow return. Although, I did get nausea as well but I would gulp as much as I could and wait a few minutes till it subsided and do it again. It has a salty sweet cough syrup taste/texture.
20's RXed with UC 08/2011. Vegan. 30-45 drops of yellow dock extract, wheatgrass 4oz daily, spiruliana tablet 2x daily, ensure complete every morning, lots of distilled water.
The Big R: 4/2014

Old Hat
Veteran Member

Date Joined Feb 2007
Total Posts : 5187
   Posted 5/21/2014 11:57 PM (GMT -6)   
Last c-scope I was instructed to mix medium-size Miralax bottle contents with 64 oz. of clear liquid. I decided to use plain Pedialyte instead of Gatorade to avoid artificial dyes & sweeteners while still getting some electrolytes. The trick to avoiding nausea, IMO, is to start the prep earlier during the day before scope, say around 2 PM. Don't overload your stomach! Use a straw to drink the mixture, but don't make it icy-cold to end up crampy. I drank 4-8 oz of the mixture about every 15 minutes then took a couple sips of plain water & clear fruit juice each time. If you don't feel up to extra sipping, just rinse your mouth with water or some non-medicinal fluid to keep getting rid of any bad taste. My goal, apart from avoiding nausea, was to clean out by 10 PM at the latest-- so that I could go to bed instead of spending the overnight hurrying to the throne room! It worked better for me than those yucky salty preps in the past. Snapple makes a white tea drink mixed with a couple clear juices that's o.k. to sip after cleaning out-- made me feel a bit less fatigued in early AM on scope day. Good luck to you! / Old Hat (33 yrs with left-sided UC; presently in remission taking brandname Colazal)

Forum Moderator

Date Joined Dec 2008
Total Posts : 16562
   Posted 5/22/2014 12:24 AM (GMT -6)   
I am definitely asking for this next time. Last time I did golytely and it was so salty and disgusting, I was sick to my stomach after the first glass and I had to drink one every 15 minutes. Just awful!!! Less is better for me. It can't taste worse than what I had last time!
Co-moderator: Ulcerative Colitis
Diagnosed with Pancolitis, Laryngopharyngeal Reflux & Migraines. Battling Extreme Exhaustion.
Currently: 6mp (25mg) + Lialda (2400mg) + Canasa (1g PM)
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