From what I understand, the biggest concern about
Imuran is with congenital anomalies. However, I'm pretty sure that's MUCH more prevalent in transplant patients than IBD patients, as transplant patients take a lot higher doses. Also, depending on how far along you are, if any "damage" is going to be done due to the Imuran, it's likely it's already been done.
There's a link to an article in the "IBD Resources" sticky thread at the top of the page you can read that explains more.
I'd talk over the risks/concerns of being on the meds (versus flaring while pregnant) with your OB, or perhaps a high-risk OB, and your GI.
If you do quit Imuran, I'd FOR SURE add in mesalamine enemas.
I'm currently 15 weeks pregnant and am on Apriso and mesalamine enemas (twice weekly).
Symptomatic remission as of May 2009
Colonoscopy in Oct. 2011 showed no inflammation
Symptoms began in Nov. 2008, about
4 weeks after birth of first child
Diagnosed with pancolitis in Jan. 2009
Apriso (Four 0.375 g pills once daily), Mesalamine enema twice weekly, multivitamin, vitamin D, probioticCurrently expecting second child, due in early March 2013
Post Edited (fruitgirl) : 9/12/2012 6:29:19 AM (GMT-6)