I was diagnosed with UC (pancolitis) in Summer 2011. Had been having symptoms for 5 months beforehand. Since then, I've more or less been on/off prednisolone constantly - starting at 40mg and reducing by 5mg weekly. Everytime I finish pred, I flare up within 2-4 weeks after I come off it and get so bad I just have to go back on it. Started Imuran in Nov 2011 and after one year of it having no effect, I started Humira in Dec 2012. Did my first four shots fine, but messed up my second lot as the needle jumped back out so I didn't get the full dosage! I am due for my next dose tomorrow which is just one injection. Just wondering if Humira worked for anyone else with severe UC and if so, how long did it take? I am currently tapering off pred and will be finished them in 2 weeks. Really want this to work I have been really strict with diet the past two weeks to see if it will help! Also taking olive oil and probiotics!