I am not familiar with the terminology gms...but I weighed 130 lbs when first placed on 6MP and my dose was 50mgm. When suffering with flares, my weight would fluctuate going down from 130 - 115lbs and I was still kept at 50 mgm.
In 2009, my flares became uncontrollable and my GI doctor increased the 6MP to 100mgm. Almost immediately I suffered horrible side effects....flu like symptoms, aching joints, etc.. My blood work was really out of control, pancreatic enzyme levels 4x the norm and liver enzyme levels 3x the norm. My doctor took me off the 6MP until all tests returned to normal, about two weeks later. He then placed me back on the 50 mgm dose. Since 6mp did nothing for seven long years I was on it, I did try Remicade (built up antibodies quickly) and then Humira (no change in 3months). I became prednisone dependent and had surgery in 2010.
I forgot to mention that I am a 5 ft 3 in woman.