Regarding FMT, there are tones of people for UC trying. You can join the Facebook group that is private from the following site:
There are no. of articles and protocols shared by people experienced.
I am almost tempted to go to the retreat myself. Before loosing colon I gotta try different stuff and FT by far is better than taking dangeros drugs that are just bandages temporary...
Testing donor is critical, people said you dont want to get other people's problem.
There are people with parasite who are asymptomatic. You want to avoid donors who have skin problems (skin problems can be developed by eating wrong food, hormonal imbalance...etc), some have kidney infections and they dont know about it, not to mention other incurable conditions that can be transmitted via FT.
I read one person who went through the FT, and got worse, and she was a vegetarian, and she got a doner who was not a vegetarian.
I know to avoid a donor who eats the food that causes you allergies. The study said to avoid pork, the allergy food for donors at least 3 days before the FT...etc. Lots of info out there.
Vets even now they do FT to fix some colon related problems for animals, but human GIs they do not. Now this is sad. Even for C-Diff there are only a handful of doctors who does FT officially because they are finding that FT cures C-Diff colitis (put one in remission when C-Diff was taking control of their life.) One doctor said in the youtube, our solution is still the antibiotics when it does not work and FT comes up as the last solution, even if they know FT fixes always in 97-99% with no recurrance after FT.
Now you take the doctor's attitude to FMT when for UC its not proven it may work. Mine was totally against it and most doctors would be.
When it doesnt work, people suggest using different donors. Some use their families because FT is personal and a little bit embarassing to ask friends but some articles say that its better to get non-related donors (that is what they do in University clinical trias after they do screening donors.) One person who cured himself went pretty drastic and he was pre-surgery stage. You can get all the info. from the internet and blogs. Lots of people try and get better but doctors are not willing to try.
I am sure whoever cure UC would be the next novel prize winner. For Peptic Ulcer, two Australian scientists after a long time trial for the breakthrough won a novel prize.
I know clinical trials in Japan showed that they were treating with combinations of 3 antibiotics (AMT methods), and the remission rate increased to 50-60%, 5-6 yrs ago. This says to me partially bacteria also has something to do with the cause of UC, because if its not for the bacteria antibiotics would not have worked. I rember before I was diagnosed with UC, I took antibiotics and as soon as I am off antibiotic, my fever came back. I am certain its realted somehow with gutt flora. I certainly dont agree with Borody that combining FT with antibiotics, based on genome science centre's study treating mice with antibiotics and doing the FT would not increase the rate of successful FT, to mimic the gutt flora of the donor.
Regarding the immune system, our immune system lies in the gutt. So I dont think its auto-immune saying our body attacks our own cell to begin with without a cause, it attacks because the gutt flora is imbalance to begin with, and cannot resolve the unknown pathogen that is getting hold of the host. With a good gut flora a person can resolve itself. I have never heard that UC person's gutt is incapable to keep our gutt flora in balance and attacks good bacteria. A person without UC symptoms can resolve the bug itself out of the body, but the person with UC cannot.
There are quite a few women who are diagnosed with UC they were diagnosed while pregnant and there are theories that our hormonal balance also has to do with UC.
Interesting about genetics. I wonder if we separate the identical twins at birth, and put them each in a totally different family with different climate and upbringing. What are the likelyhood of developing IBD. Hmm 40-60% is not 95%. What are other 40-60% factors that causes UC? I understand it has to be the perfect storm. I wonder what are those factors. Food is also a key, after all UC is the disease of an industrialized world, loaded with antibiotics in beef, pork chickens, and milk. I think dairy is not the problem, its the way they feed kettle, they do not eat grass anymore, they feed grains to kettles that cannot tolerate, and needing antibiotics to keep them healthy. I am sure that as soon as people started to feed food to animals we eat, those livestocks that are so unhealthy to begin with loaded with antibiotics and hormons, that is the problem to begin with.
I hope I was in medicine or biologist to begin with, or got UC when I was teenager, at least I have a passion I can pour into, fixing my own problem because no one would fix this.
Diagnosed since 2012 Janauary.
Hospitalized for 3 months, without food for 1 full month!
Current Medications: Prograph, Sulfasalazine, Probiotics via Prescript
Medications Tried: Asacol, Prednizone (enema and oral form), Pentasa (enema and oral form), Adacolumn
**Currently thinking towards surgery.