1. Nope. You'll be sedated so you won't feel any irritation from the scope. If you have internal ones the doctor will be able to see it with the scope and let you know.
2. Never had a colonoscopy during my period but I have had sigmoidoscopies while wearing a tampon and it wasn't a problem. I'm sure someone at your doctor's office can answer this question for you definitively when you make the appointment.
dx'ed UC pancolitis 5/12
past meds: asacol hd, VSL#3, apriso, rowasa, xifaxan, 6mp, cortifoam, pentasa, cimzia, canasa, butyrate, flagyl, cipro, prednisone, remicade, methotrexate, cholestyramine, cortenema
current meds: butyrate
step one: colectomy, end ileo 1/16/13
step two: j-pouch construction, loop ileo 5/1/13