While reading through my old thread and looking for the reasons for neurotransmitter imbalances,one of my statements is.
What I think I know on diet is this.
First you cannot make serotonin without trypotphan,and possibly melatonin not sure on that.
If you eat a lot of protein you get tyrptophan,but will not be absorbed well,because it competes
with the other amino acids.
But if you eat carbs at the same time then you get an insulin spike,then you get an increased
ratio of tryptophan to other aminos and then it can be absorbed into the brain at least.
So to lower tryptophan my guess is not to combine carbs with protein,and possibly excess protein or
But in UC there may also be someting wrong with SERT in the gut,possibly due to inflammation.
If we assume for one minute that an imbalance in neurotransmitters is a possible cause of UC. Then.
Food combining the way many normally eat may be causing the problem in the first place, that nice steak sandwich my son used to eat 10 oz or so of beef on a 12 inch roll.
The great old american standard meat and potatoes,how about beef stew,the great american sandwichs of all types. Pizza,thankgiving dinner,turkey,bread filling,mashed potatoes,then through in some bread,pie.
Bacon and eggs might be fine,but then you add toast and home fry's.
Or how about a McDonalds breakfast sandwich.
Seems the american/western diet pushes for an unusually high tryptophan absorption,combine this with
some high serotonin foods such as bananas,walnuts others.
Also it seems low glycemic foods better,high glycemic foods like sugar give bigger faster insulin spike,which
might be the sugar connection to IBD. So your high protein meat dinner,with cherry pie,sugar in your coffee,glazed sweet potatoes,not good,how about glazed ham. Combine this with western cooking methods
and you might have a real mess going on in your poor colon.
Also butyrate in the colon down regulates SERT,somewhat of a paradox since butyrate is a food for colon cells.
This perhaps a reason SCD and Paleo works on some people,high protein low carb=less tryptophan being absorbed,but you are still eating some carbs and probably both at the same time,which leads to tryptophan being absorbed. Perhaps these diets would work much better if you eat protein and carbs at different times.
Will look more into food combining and neurotransmitters,hopefully will find real science as opposed to junk.
Looks like I have a thread on this in the past,might have to start trying this.
Not talking about food combining in the traditional sense,based on digestion of protein and carbs in the stomach
and whether they digest properly,dont really know if those theories are true or not.
There is also the possibility that eating carbs at any time gives an insulin spike and makes more serotonin,from
existing trypotphan,from he last meal. Need to try and look into this.
Bottom line,perhaps we can balance neurotransmitters,just by eating differently.
Post Edited (Old Mike) : 4/12/2013 4:00:40 PM (GMT-6)