There are some folks on the forum who are really well-versed in herbal remedies
I cannot tolerate mesalamines either. But in my case it is almost a blessing in disguise because my IBD can be controlled with natural supplements without the side effects from meds. Government sponsored research shows that it can indeed work for some people.
I take a variety of supplements but my mainstay is powdered psyllium seed and prescript
ion VSL#3DS probiotics. But supplements aren't very effective for me unless I also monitor my diet, not with the standard SCD but a food diary that told me that I must restrict food triggers like gluten and certain vegetables.
Below is a link to some government research. Besides supplements another drug many have found to help with IBD is LDN. I don't know what to tell you if LDN and natural supplements with diet modification are ineffective for you. I guess you would have to graduate to the "big gun" meds?www.healingwell.com/community/default.aspx?f=38&m=2204683www.ncbi.nlm.nih.gov/pubmed/10022641CONCLUSIONS:
Plantago ovata seeds (dietary fiber from psyllium seed) might be as effective as mesalamine to maintain remission in ulcerative colitis.