There's no harm in seeking a second opinion. Do you live in or near a major city? I tend to agree with gary that as far as UC goes you really don't need a CC or Mayo GI. A GI who specializes in treating IBD at a major teaching hospital would be more than helpful.
That said, your husband's experience sounds VERY similar to mine. There are alternative therapies and diets that it sounds like he hasn't tried yet, but if I were him (and you) I would take this time to start warming to the idea of surgery. There are risks associated with any treatment, and they are probably greater with surgery, but there are simply no
other treatments for UC with a rate of effectiveness as high as colectomy. Even prednisone doesn't work as well or as often. Depending on the center where it's performed, j-pouch satisfaction can be as high as 95%. There are many people here, on the Ostomies board, and out there in the world who have had our whole lives turned around because of surgery. If he chooses to go that path, that
is when it would be an absolutely terrific idea to go to Cleveland Clinic.
dx'ed UC pancolitis 5/12
past meds: asacol hd, VSL#3, apriso, rowasa, xifaxan, 6mp, cortifoam, pentasa, cimzia, canasa, butyrate, flagyl, cipro, prednisone, remicade, methotrexate, cholestyramine, cortenema
current meds: none!
step one: colectomy, end ileo 1/16/13
step two: j-pouch construction, loop ileo 5/1/13
step three: takedown 7/31/13