Posted 6/13/2013 6:37 PM (GMT -6)
I just started the new replacement for Asacol about 1-2 months ago. It is supposed to be bioequivalent to Asacol. However, it is now a caplet stuffed inside a capsule. For me this makes it not distribute to the same part of my colon it used to, and because it is such a thick capsule, often doesn't disintegrate by the time I have a bowel movement. If you are taking this medicine I encourage you to check to make sure that this capsule is disintegrating. Part of what made Asacol effective for me (more effective than Pentasa for instance), it is distributed lower in the GI track, but with another layer on it, it is hardly distributing at all before I pass it.