Jessica Marie said...
I have yet to be able to find how greatly Remicade increases your chances of developing cancer.
Slide 21: Main Side Effects of Anti-TNF Treatment
I think malignancy is the most concerning to both patients and providers and families when you think about
starting a medication that might actually cause cancer, which is a scary thing to think about
. But to remind you of the baseline risk, meaning those people walking around on no medications at all of non-Hodgkin’s lymphomas, about
2 people out of 10,000 (or 0.02%). On the immunomodulators, it’s about
4 people out of 10,000 (or 0.04%). If you’re using anti-TNF medications along with immunomodulators, although the risk is a little bit higher, it’s still about
6 people out of 10,000 (or .06%).
Slide37: Putting Risk in Perspective
The chance of dying over your lifetime from a biking accident is 1 per 5,000; drowning, 1 per 1,000. And believe it or not, in the US, the chance of dying in a car accident is about
1 out of 260. The chance of dying from cancer is 1 out of 8, and the chance of dying for heart disease is 1 out of 5. Now, remember this isn’t patients with Crohn’s disease. This is people in general. So when we’re talking about
side effects of medications on the order of 1 per 10,000, 6 per 10,000, we’re taking extremely small risks.
Source: Balancing the Risks and Benefits of Treatment For Inflammatory Bowel Diseases
by the Crohn's and Colitis Foundation of America: