I've been told by several drs that remicade or humira are safe for men to be on while trying to get pregnant. I guess you need to decide what you are comfortable with. The message I received is that it is worse to have active disease than to be on an anti-tnf. My first dr told me of a male patient who could not get pregnant with his wife, ended up going on remicade and still no luck with preganacy and then to take care of some peripheral arthritis he added on sulfasalazine and ended up getting his wife pregant with a healthy baby. You never know.