I've done it. www.23andme.com
My results with regard to Crohn's and UC actually matched what the Prometheus Panel had to say about
me, so if you're curious about
the Prometheus Panel and insurance won't cover it, 23 and Me might be a good compromise. For the curious, according to the known genetic markers, I'm at a significantly decreased risk of developing both UC and CD. Oopsies.
My whole family did it -- it was a running joke that my parents were hesitant to do it (pretending to be hiding a big family secret, haha) -- and the results were... interesting, but not super surprising. Aside from my being SUPER UNLIKELY! to get IBD, we saw the usual stuff about
all of us being more likely to have AI diseases, etc.
I found it interesting to compare my genetic markers with my mom's, because she is my only close relative who also has IBD, but she has Crohn's -- and she has several Crohn's markers that I do not. It actually was sort of a relief for me because I've always worried that I'm more likely to have Crohn's colitis than UC because of my family connection. But apparently at least some of the genes that SHE has that we think of as "Crohn's genes" weren't passed on to me.
dx'ed UC pancolitis 5/12
past meds: asacol hd, VSL#3, apriso, rowasa, xifaxan, 6mp, cortifoam, pentasa, cimzia, canasa, butyrate, flagyl, cipro, prednisone, remicade, methotrexate, cholestyramine, cortenema
current meds: none!
step one: colectomy, end ileo 1/16/13
step two: j-pouch construction, loop ileo 5/1/13
step three: takedown 7/31/13