I have my first Remi infusion today. I know the stats so I am rather pessimistic about what it will do for me, but am really hoping this brings me some relief, even if temporary. I have been reluctant to go to a biologic for many of the obvious reasons, but I also liked knowing that there was something else out there. Anyway, I have to do something. I spend way too much time in the bathroom, have tremendous cramping/pain, and have lost 15 pounds in the past month... and I didn't have that much to spare.