What options are available to you? Well, first let me say I hope the increased frequency of your Remicade infusions helps you out, give it some time but not too long. Remicade is currently the most effective biologic available for uc but the odds are something like 67% of people feel better within the first few weeks and then 37% have a sustained remission from it over the long term.
Humira has helped some here, but the success rate is much lower than remicade according to clinical study numbers. I know there are some here who use Humira and it has worked well for them, so I wouldn't count it out. Just know that both Remicade and Humira aren't silver bullets that work for everybody all of the time.
There is some talk on here about
another biologic medication called Simponi but I am not all that familiar with it; I think the odds are about
as good as Humira; not so great.
There's another biologic coming out next year called Vedolizumab that is supposed to be as good, if not better than Remicade, and the studies were run on people who didn't succeed on another biologic med. I think the sustained remission rate was mid 40's over the longer term (better than Remi's high 30's). It gives some hope for the future but the exact available date isn't disclosed yet, not so good if you need it now.
If medications fail then the next step is a consult with a surgeon. Although, you might want to have a consultation with a surgeon for information purposes well ahead of that time, just to see what options are available to you, and to answer your questions. Better to be informed ahead of time than to suddenly need surgery and have no time to research it. Bootstrap has a good blog talking about
it, if you wanted to read up on the process and her experience with it: http://ronnielee-fightingforit.blogspot.com/
I hope she doesn't mind me shamelessly plugging her blog but it really is a good read.
35 yr old male/ proctosigmoiditis
Rx: Daily 75mg 6MP + 5g Lialda + Rowasa + 12mg Prednisone (holding waiting for Remi approval)
Diet: Diet mods and supplements haven't done a thing for me.
Having uc is like having a monkey on your back; it's annoying, painful, and it involves sudden and unexpected poop.
Post Edited (iPoop) : 9/9/2013 1:01:15 PM (GMT-6)