Small intestine transplants have been performed infrequently for many years for patients with short bowel, including Crohn's patients. In the Crohn's patients the new intestine DOES eventually develop active disease, but it's a huge improvement in quality of life for the intervening years.
As far as I know -- and I have searched high and low -- large intestine transplants have never been performed. When you think about
all of the man hours involved in an organ transplant (harvesting, transporting, surgical teams, recovery, follow up care, etc) and facilities etc, it makes no sense to transplant an organ that can easily be lived without. Because large intestine transplants aren't performed we can't know for sure that inflammation would return in the new colon, but we have evidence that inflammation returns to new small intestine, which does not reflect favorably on the idea of colon transplants.
dx'ed UC pancolitis 5/12
past meds: asacol hd, VSL#3, apriso, rowasa, xifaxan, 6mp, cortifoam, pentasa, cimzia, canasa, butyrate, flagyl, cipro, prednisone, remicade, methotrexate, cholestyramine, cortenema
current meds: none!
step one: colectomy, end ileo 1/16/13
step two: j-pouch construction, loop ileo 5/1/13
step three: takedown 7/31/13