I can't see any indication that trial went beyond 54 weeks - or just over 1 year.
To be honest, I don't understand why concurrent steroids, immunesuppressants and 5-ASAs were allowed, unless the drug manufacturers were trying to cook their results (nah). 39% were in clinical remission at 8 weeks, but another 35% were in clinical remission at week 54. I find it strange that there is such a large time gap between the two groups. Presumably the remainng 26% never reached remission.
I dunno. Maybe Remicade does take longer to work in UC than in Crohn's, but a year to reach remission is still something I have never heard of. I've also seen plenty of people say that Remicade worked like a charm for the first few infusions, then they lost response and it stopped working.
I really think that study was trying to cook the results a bit by including patients who just happened to reach remission after a year. But you can't be sure it was down to the Remicade. Many, many people would come out of a flare up naturally, if left to their own devices. (It happened to my brother a few months ago. He has Crohn's/indeterminate IBD. Anyway, he claimed the steroids weren't working this time, but he still seemed to come out of his flare-up just the same anyway, and without any other change in meds.)
Post Edited (NiceCupOfTea) : 4/4/2014 7:04:08 PM (GMT-6)