The bad gene thing is sort of fatalistic and simplistic. You need to blame mommy's genes, the stupid way she raised you and all the stupid things you did..and dad moving you to Winnipeg when you were 4. Fix that with a gene splice...I don't think so.
This isn't Freudian psychoanalysis we're talking about
here. Think you got a tad mixed up somewhere. We're not talking about
what mommy and daddy did when you were 5 years old; we're talking about
gene mutations that happened before you were born. (Or maybe after, but still entirely unrelated to childhood trauma.)
But I guess saying IBD is in your genes is a dirty idea on this board. Even though there are hundreds of hereditary diseases which are passed down through the genes.Well there is at least some genetic component of the disease; that we know for a fact. Im pretty sure its not causal though, it just increases ones susceptibility to the disease.
As for whether or not there will be a cure, coming form someone who actually works in a lab researching the etiology and pathogenesis of IBD, Im all but certain there will be a cure "relatively" soon. I look at the work my colleagues are doing and it really inspires hope! There are exciting breakthroughs every day, and we are constantly inching closer to a full understanding of the disease.
Personally, I think the cause/cure is going to involve the interaction between the mucosa/immune system/microbiome, which is good because there is so much research going into that area now a days. One such example that I am extremely excited about
is a study at McMaster University here in Canada that is doing an RCT with fecal biotherapy. Not only are they doing that, but they are also looking at the differences in the microbiome of responders and non-responders to understand what makes some ppl respond and others not. This data combined with the advent the "poop pills" from Alberta (aweful name I know) may provide us with a treatment that will, in some ways, mimic what the eventual "cure" will do.
Only time will tell, but I am very hopeful!
UC since Sept 2009Therapy
Remicade - 400 ml