Im a 21 year old woman with two kids.I contracted C DIFF back in February of this year. I recently was just diagnosed with it yet again this past week. I was put on 500mg of Flagyl, three times a day. After four days everything seemed to be just peachy (considering how awful c diff is), when I noticed a throbbing at the base of my skull. It became so intense I assumed I was having a reaction to the medication and switched to Vancomycin, another alternative for c diff. For those of you unaware, it is a VERY expensive medication. I paid $433.53. After two days on the Vanco, I noticed my head aches were getting worse and worse. Then the pressure started. It was so intense, it still is. I can feel it from behind my eyes and the roof of my mouth. The pressure is so intense I feel like I'm dying. Had an MRI done to rule out an aneurysm or something, it was clean. Got a lumbar puncture done, still nothing showed up. It's been five days, the pain/pressure has not let up. At times it feels like my brain is being twisted around like a wet washcloth. It has taken a toll on my life and totally consumed my whole life. I thought it was an allergic reaction to the flagyl, but I'm not so sure. If anyone has had these symptoms as well I'd appreciate your input. Thanks so much.