Also been doing a little thinking.
If I remember correctly around 28% of none IBD peoples colons/intestines contain MAP.
Therefore it would seem just MAP is not sufficient to cause IBD.
Take my case,quit smoking in 1977 UC 1980, also moved into house 1/4 mile from working dairy farm in 1979, did drink the milk, my UC son born 1978,he drank the milk when old enough.
Now take my wife. Please!!! LOL
She has risk factors, she quit smoking at the same time, I did.
She drinks about a 12 pack of diet coke a week,now known for sure that artificial sweeteners disrupt gut bacteria.
She lives with me, most likely a possible risk factor.
Wife does not drink milk,but likes cheese.
Anyhow she has at least two known risk factors,possibly 3, yet no IBD or IBS.
So other than genetics,it might seem that to get IBD some additive combination of risk factors need to be
in place for IBD to manifest. We have so many protective mechanisms it is hard to believe we get it at all,and when you look down the immune and biochemical pathways so much has gone wrong it is just amazing. But again
suspect the immune response has created much of the mess.
Is MAP an additional factor, wish I knew.
Post Edited (Old Mike) : 9/22/2014 4:41:04 PM (GMT-6)