remicade vs entyvio

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Regular Member

Date Joined Jan 2014
Total Posts : 422
   Posted 1/15/2015 7:59 PM (GMT -6)   
I guess my next option is either remicade or entyvio. Which one is cheaper and more exffective. I have a very high deductible and being single earner cost is a major factor.

Veteran Member

Date Joined Feb 2011
Total Posts : 4046
   Posted 1/15/2015 8:09 PM (GMT -6)   
Remicade. But you need to take it with another med to prevent antibodies. Entyevo is brand new and expensive. Remicade may be a few percent more effective, but no direct comparison study has been made. But compared to placebo, Remicade seems to be about 4% better.

There is some sort of Remistart program that might help. If you cannot get an assistance program, then either drug, I think you are going to have to meet your full delectable with the 1st few treatments - hopefully you have a cap.
11/08: ischemic colitis and scope perf colon. 12cm colon/ileocecal resected. IV antib:sepsis.
01/10: Dx: Mod. UC pancolitis. Rx: Lialda 3x.
02/11: Major flare w/antib:sinus. Rx: 40mg Pred taper. 6mp.
07/11: Histol remiss rt/trans; worse sigmoid. Rx: Rowasa & hydrocort
Curr: 1-2 soft-formed stool, no urgency: Lialda 2x, NO PRED, probiotics, Vit-D/C

Veteran Member

Date Joined Aug 2012
Total Posts : 9088
   Posted 1/15/2015 8:33 PM (GMT -6)   
First you need to check with your insurance to see if either one are covered. They may make you do something else. Many don't cover Entyvio.
Pentasa (500mg) 2 pills X 2; VSL 1 pill X 2; Prescrip Assist Probiotic 1 pill X 2; Grape seed extract (1)400mg X 3; Vitamin D3 (1) 5,000 IU X 2; daily generic Allegra; DAO as needed due to dietary histamine intolerance

Gave me trouble: Zymactive, Renew Life Probiotic 80 billion, Florastor, high histamine foods

Veteran Member

Date Joined Oct 2014
Total Posts : 730
   Posted 1/15/2015 9:44 PM (GMT -6)   
Remistart covers $10,000 a year with a $5 co-pay. Last year it was $8,000 with $50 co-pay. I would also check out entyvio warriors on fb. Lots of feedback regarding results, side effects, cost and financial assistance.
42 yo; left-sided uc dx 2001
asacol max dose for several years
prednisone and rowasa when flaring
remicade since 2009
zofran and canasa
currently flaring

Regular Member

Date Joined Jan 2014
Total Posts : 422
   Posted 1/15/2015 10:12 PM (GMT -6)   
Tx everyone

Forum Moderator

Date Joined Aug 2012
Total Posts : 11813
   Posted 1/16/2015 6:15 AM (GMT -6)   
Most insurance requires you to fail at least one anti-tnf medication before allowing you to go on entvyio.
Moderator ulcerative colitis
M, 36, proctosigmoiditis
Rx: Remicade 5mg a kg every 8 weeks, 75mg 6MP, twice a week Rowasa
Diet: Diet mods and supplements haven't done a thing for me
My posts are best enjoyed with a HEAVY Boston accent, e.g., Hey, wheah's Pawlie? Last I sawr him, he was pukin next to a pahked cah westa Wihsta.

Veteran Member

Date Joined Mar 2008
Total Posts : 1202
   Posted 1/16/2015 8:08 AM (GMT -6)   
I vote Remicade too, and either drug will eat up whatever deductible you have. The Remistart folks are great, and it slows down the pain, and helps a lot.
I am concerned about upper respiratory issues with your DD on Remi. Make sure you have that asthma under control and there are no infections before beginning. Also, get any vaccines up to date that use live viruses.
Don't wait too long either, I can't speak to the cascade if FMT fails, but I do know how hard a flare is to get under control when a young person mounts an impressive response. Hang tough.
Daughter, 21 diagnosed 1-08 w/ UC
Drug sampling: Asacol,Cortifoam, 6mp,Colazal,Rowasa,PPI'S, Flagyl, Pred.,Diet not directly impactful.Remi w/adjustments= remission 4 yrs, re-remission with Tacro 6 mo. Back to Endocort, Uceris,Canasa, hospital(#10), Pred. Pancolitis via scope.Retried Remi. Entyvio, loading doses didn't stop train-surgery Step 1, 8/28/14 Step 2(of3) Dec 5.

Veteran Member

Date Joined Dec 2003
Total Posts : 642
   Posted 1/16/2015 8:19 AM (GMT -6)   
Remicade will work faster than Entyvio. Take that into consideration as well. Most likely insurance will require you try and fail Remicade before approving Entyvio. Google your insurance company name and "clinical policy bulletin Entyvio" and you should be able to see what they require. Both drugs have co-pay assistance programs. Entyvio will pay all but $50 for each infusion, up to $6500/year.
38-year-old male, Diagnosed with Crohn's in 1989 at age 12
Happy on Humira for 9 years until August 2013
Failed Remicade, Cimzia, Imuran, 6-MP, MTX
Ileostomy April 2014
Started Entyvio July 2014

New Member

Date Joined Sep 2014
Total Posts : 14
   Posted 1/16/2015 10:28 AM (GMT -6)   
It should be noted that you may get worse on Entyvio while it begins to work, increasing your chances of worsening the flare to the point where you can't get out. Remicade works very quickly, so that's what I would go with first.

Forum Moderator

Date Joined Dec 2008
Total Posts : 15924
   Posted 1/16/2015 10:58 AM (GMT -6)   
I don't even think entyvio is approved for pediatric use, remicade is. Remicade is more effective from what I've seen.
Co-moderator: Ulcerative Colitis
Diagnosed with Pancolitis, Laryngopharyngeal Reflux & Migraines. Battling Extreme Exhaustion.
Currently: prednisone + remicade
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