That's an interesting study.
Seems like you are on the right track. But it is probably just not the inner mucus barrier,but it could be.
The amazing this is that we have so much defense, yet we get UC, something has gone very wrong.
The stool composition and construction layers are also not correct, as Swidsinski calls it
I am still on one clove a day,If I see nothing in a week will go to two.
Here is my stuff from last week on antimicrobial peptides,they should go after biofilm.
Looks like from the below info that a 3 pronged approach has a chance.
Vitamin D,cucurmin,and butyrate.
here is a cached version
looks like oral vitamin D can upregulate at least in the skin cathelicidin
seems that as we know there is a IBD vitamin D connection
wow now I find that butyrate also induces,is there a connection here with biofilms and our loss
of butyrate producing bacteria
well it is upregulated in UC but not crohns, is it upregulated enough
and now I find curcumin is able to induce this article also says that cysteine proteases cleave it
and we know that protease inhibitors can induce remission
seems that nothing is all good, they have a bladder inflammation model using ll-37
high salt concentration and PC inhibit, yes PC at least bacterial PC
dose many things and all perhaps not good
induction by curcumin not vdr associated
butyrate crohns trial just some info
http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2036.2005.02639.x/pdf<!-- Edit -->
Post Edited (Old Mike) : 4/8/2015 2:51:18 PM (GMT-6)
Post Edited (Old Mike) : 4/13/2015 5:29:11 PM (GMT-6)