olivia lynn said...
they admitted me just to observe me over night (going home at 12ish hopefully) they have me on benadryl, ibuprofen, iv fluids, and toradol to control things. they're almost positive i have serum sickness (not sure how its spelled), anyone can get it whether its a vaccine or an infusion. it's just a reaction to whatever youu receive. i would do what i did and go to the er and get checked out from there! let me know what happens or if you have anymore questions. my email's on my profile if youu want to shoot me an email
Here's an article about
infusion related reactions to infliximab/remicade. The article is about
psoriasis use, but the infusion reactions would be the same.
Review and Expert Opinion on Prevention and Treatment of Infliximab-related Infusion Reactionswww.medscape.com/viewarticle/580215
Delayed reactions are reactions that occur between 24h and 14days after an infusion, the majority occurring after 5-7days. In most cases symptoms include arthralgia (pain in joint), myalgia (pain in a muscle or group of muscles), influenza-like symptoms, headache, tiredness and 'rash' or urticarial (hives).
Serum sickness is an allergic reaction to an injection of serum, typically mild and characterized by skin rashes, joint stiffness, and fever. It's a type III hypersensitivity reaction. Typical symptoms of serum sickness are rash, fever, and polyarthralgias (aches in the joints, joint pains, and multiple joint pain) or polyarthritis (arthritis that involves 5 or more joints simultaneously). These symptoms begin 1-2weeks after first exposure to the agent responsible and resolve within a few weeks after discontinuation. A delayed infusion reaction to infliximab clinically imitates serum sickness.
Treatment with infliximab can result in the development of human antichimeric antibodies, mostly called antibodies to infliximab (ATI). It has clearly been shown that the presence of ATI increases the incidence of infusion reactions.
Moderator ulcerative colitis
John, 37, uc proctosigmoiditis in remission
Rx: Remicade 5mg/kg/8 weeks and 6MP 50mgs/day
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Post Edited (iPoop) : 9/18/2015 9:20:00 AM (GMT-6)