My experience is I got my first positive response a week after my second infusion of remicade, a much bigger response after my third infusion, and slow and steady improvements until I reached remission a year after starting remicade.
Remicade is a protein designed to block an immune signaling protein called tnf-alpha, which is used by our immune system to say "attack over here". The more muted you immune system's call for an attack becomes, the less inflammation is caused in your large intestine, and that allows your body to begin healing and will result in your uc symptoms improving. Healing takes time. The purpose of the loading doses is to get remicade up to a therapeutic range within your body. I would ignore a fading response during loading doses, but not during the maintenance phase as dose and frequency must be sufficient then to prevent a fade in response (and adjusted accordingly).
Hang in there, you might have a response, but as others say it might be to soon to know for certain.
Moderator ulcerative colitis
John, 37, uc proctosigmoiditis in remission
Rx: Remicade 5mg/kg/8 weeks and 6MP 50mgs/day
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Post Edited (iPoop) : 9/22/2015 6:37:46 AM (GMT-6)