Both are ph based, different chemical coating, different target ph.
Asacol tablets are coated with Eudragit S. Pentasa beads and tablets have a coating of ethylcellulose.
The USP dissolution (disolve) methods are different for Pentasa extended-release mesalamine capsules (performed at pH 7.5 only) and delayed-release Asacol tablets (performed at pH 1.4 for 2 h, pH 6.0 for 1 h, and finally at pH 7.2).
Moderator Ulcerative Colitis
John, 37, UC in histological remission
Rx: Remicade @5mgs/kg/8wks + 6MP @25mgsWell, that went down like a loud fart in church...
Post Edited (iPoop) : 12/30/2015 1:07:50 PM (GMT-7)