Question - Canasa/ Petroleum Jelly

Hey all - so been using Canasa suppositories for about a month or so, and it was always a bit difficult to use, so I started using Petroleum Jelly to assist the last night or so. Just looking at the patient info and seeing that it says specifically not to do that. So of course I feel like an idiot about not looking first. Anyway - does anyone know why?

Thanks - fell well everyone

Probably any kind of lubricant could prevent the medication to have optimal contact with the colon mucosa. When I've used supps I found that melting a little the side of insertion with hot water it's the best way to make easier to insert it.