i know this is the uc forum, but thought i would give a bit of background first in case i get lucky & some of you are familiar with these other conditions...
i was diagnosed with uc back in 2012. while it hasn't been horrible - i only go to the bathroom 2 - 3 times a day, psyllium husk keeps things formed, but urgency is an issue & occasionally i do see a little fresh blood. i had a colonoscopy done 2 weeks ago & it showed some left sided inflammation, really bad internal haemorrhoids & a tear in my colon that the doc put clips in to close up.
in april of last year i was diagnosed with thrombocyt
openia (ITP). and more recently hypereosinophilia. i had a liver biopsy done last month & my doc said he has never seen a liver packed so full of eosinophils.
BUT all three of these conditions seem to respond very well to steroids (prednisone). i'm on 20mg right now & feeling pretty decent. however we all know there are some pretty nasty side effects to being on prednisone long term. my hematologist & GI want to start me on 6mp as they say its similar to prednisone in its full body effects & can treat all 3 conditions without all the nasty side effects.
however, i'm reading online about
liver issues which concerns me - as of yesterday's physical exam by the hematologist my liver is still slightly swollen, although not painful. it has been showing up strange on scans all year, possible fatty liver & obviously affected by the hypereosinophilia. when i'm not on prednisone my blood work shows my liver enzymes start to get elevated along with my eosinophil count.
i'm also reading about
infertility which concerns me as my boyfriend & i would like the option of having a child sometime within the next several years. i also read that apparently it interacts with mesalamines (asacol)?? oh & apparently in a small percentage of people it CAUSES ITP!! although my hematologist says he has several ITP patients taking azathioprine for ITP & i know that's very similar to the 6mp so obviously it must work for that condition. maybe i just need to get off the internet?
so i'm just wondering what your experiences with 6mp were. did it work well for you & how long? are there any minor side effects to be prepared for? are the liver & infertility issues common? would it permanently damage my liver, or does the liver recover after stopping the medication? any insight & advice would be much appreciated before i have to make this decision!!
Post Edited (handfulofrain) : 3/14/2017 7:00:50 AM (GMT-6)