Hi Maid Marion,
I started out a year ago on Remicade, and Methotrexate was introduced with my second dose. The Methotrexate actually induced my symptoms, so having had two tries at restarting it with no success, I am now on mono-therapy with Remicade and am more or less symptom free.
My GI didn't initially want to try mono-therapy, but as I wasn't developing antibodies and my inflammation had gone down, he admitted it was looking like the methotrexate was the culprit. It only took a week or so after coming off that the symptoms subsided and the Remicade has been wonderful since - it may be worth discussing a trial of this with your GI?
May 2016 DX changed to Crohn's Disease
Symptoms 11 yrs, Dx Jan 2014 UC 15cm, extended to 21cm Feb 2016, 40cm April 2016 - Current Dx IBD-U
Four tapered course of Prednisolone (Sept 14, Aug 15, Nov 15, April 16).
Olsalazine - 4g daily
Methotrexate - 15mg/week
Hospitalised 1wk April 16
Acidophilus 20billion - 1 capsule daily