Posted 4/13/2017 7:58 PM (GMT -7)
"Considering that curcumin is a readily available, safe and a cost-effective botanical, there is a growing interest in exploring its clinical efficacy individually or as an adjunctive treatment for managing and/or treating UC and subsequently improving the overall quality of life for patients with this inflammatory disease.
Although curcumin is a well-established anti-inflammatory agent, the exact mechanism(s) by which it attenuates inflammatory burden in diseases such as UC remains unclear. Herein, we demonstrated that curcumin exhibited significant anti-inflammatory effects in a mouse model of dextran sodium sulfate (DSS)-induced colitis.
In particular, a unique formulation of curcumin containing essential turmeric oils (ETO-curcumin) displayed greater anti-inflammatory efficacy compared to the standard curcumin, as evidenced by the reduced disease activity index (DAI) and changes in gene expression alterations of the inflammation-related genes, highlighting that ETO enhances the anti-inflammatory efficacy of curcumin.' - https://www.nature.com/articles/s41598-017-00812-6