I am going to do combination therapy for CD ileitis, improperly diagnosed as UC for ~11 years. I'll try to bullet-point my questions and if anyone has experience or knowledge, I'd greatly appreciate it:
- I've discontinued asacol HD which I'd been taking for ~7 years. Should I notice a change?
- I am not scheduled for my first infusion for 9 days, so I am continuing my mesalamine rowasa enemas nightly in addition to the imuran...i understand this is ok, yes?
- I am taking 150mg of imuran, on day 3. So far I've noticed looser BMs but not greater frequency. Is this a common side effect? Will the side effects pass as my body adapts to the new medication?
- what should I expect when I start infusions of remicade and discontinue my rowasa enemas? I am most nervous about
this, as it has helped my symptoms more than any other treatment I'd ever had and still is effective at minimizing urgency and frequency...
Overall I don't feel well, which is why I'm going full bore with combo therapy. That said, I am better symptomatically than I've been during other flares. Should I expect a step back before the combo therapy moves me two steps forward (ideally)? Is there a rule of thumb on how this all should feel?
I posted this in the CD forum but figured I'd try here as well. Since we take the same meds and most of my activity is in my colon. Once again all feedback/suggestions/answers are appreciated
32 yr old Male. Diagnosed with UC in early 2006. DX change to CD ileitis in 2017. Also living with Hiatal Hernia and GERD.
Taking: Imuran (150mg), VSL#3 Tablets, Librax, Rowasa nighty.