Generic for Lialda

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Regular Member

Date Joined Jul 2011
Total Posts : 103
   Posted 8/4/2017 2:46 PM (GMT -6)   
I have been on Lialda for about 5 years. I just learned that the pharmacist that a generic for Lialda just came out. She said it's not available for this month's refill, so I will be getting the Lialda brand-name again. I'm stable, and just finished chemo and radiation for breast cancer. I'm concerned about messing up what is going well. Anyone start taking the generic already? All is well? Are the pills still large? I have to take 4 daily, and I sure wish they were smaller -- I pray they are not any larger!!
40 yr old Female. SAHM to 2 children.

First UC signs Nov 2010 at 16 wks pregnant; Jul 11 diagnosed Pancolitis after childbirth.

Currently: 4 Lialda at night. VSL#3 DS 1 packet per day, w/Kefir. Alpha-Lipoic Acid.Fighting breast cancer
Past: 10 Fecal bactiotherapy treatments Aug 2012, Came off Aza!; Prednisone; different mesalamines. 1 colonoscopy, 1 flex sig, 2 d&c, 2 c sections; mastecomy

Forum Moderator

Date Joined Aug 2012
Total Posts : 12774
   Posted 8/4/2017 2:52 PM (GMT -6)   
All I know is this, still says 1,200mgs per tablet so the size should be similar:
Moderator Ulcerative Colitis
, 39, UC Proctosigmoiditis
Rx: Remicade @5mgs/kg/6wks; daily 75mgs 6MP, 4.8g Lialda, and 2X rowasa

After fearing farts during a bad flare, i now fart with pride and and reckless abandonment

Regular Member

Date Joined Oct 2016
Total Posts : 40
   Posted 8/4/2017 3:44 PM (GMT -6)   
I actually saw a picture of the generic on Instagram and they look exactly the same. I totally feel you on the pill size. I HATE swallowing large pills and have to choke 4 of those suckers down every day.
36 year old female, Diagnosed with ulcerative procitis 9/16. Currently in second flare, 4 Lialda a day, Hydrocort enemas. Diet - gluten free and vegetarian, Culturelle probiotic.

Regular Member

Date Joined Jun 2007
Total Posts : 364
   Posted 8/12/2017 1:06 PM (GMT -6)   
I just got home from the pharmacy picking up my son's Lialda and was told that my insurance prefers he switch to generic. That was a big surprise because I thought Lialda was good until 2020. I always hate changing things so asked if they could run the Lialda through and thankfully it was approved, but I know we will face this again next month when he ages out of our insurance and has to buy it under his own.

I'm looking forward to hearing how patients do on the zydus version and I'll let everyone know how it goes if/when we are forced to switch.

Mom of Son 25 UC dx at age 10, Lailda x3, Azasan 175 mg, Zyrtec D, Iron, Protein Supplements.

Daughter 18 UC dx at age 8, Colazal x6, 6MP 25/37.5 mg, Prozac, Florastor, Culturelle, Iron, Vit/Min.

New Member

Date Joined May 2017
Total Posts : 5
   Posted 9/8/2017 7:17 AM (GMT -6)   
I have been on the Zydus version for almost a month and I hate it. I was very torn accepting it when I noticed it wasn't Lialda but the cost difference pushed me to try it.. Bad move now that I look back. My symptoms have started to come back; mild discomfort in my lower back all day long, mucus in my stool and urgency has increased however no blood yet. I also take 1000mg Canasa every other night. My diet has stayed exactly the same and stress levels are no different. At this point the only thing that has changed was the switch from Lialda to the Zydus Mesalamine Delayed Release Tablets. I can't say 100% the Zydus version is the cause but its literally the ONLY thing that has changed so I point my finger at it. I have refilled my prescription and am back on Lialda.

I can't say if others will have my same results but wanted to share this so people are aware smile

New Member

Date Joined Jan 2018
Total Posts : 2
   Posted 1/4/2018 10:57 PM (GMT -6)   
Same, when I took the Zydus version I noticed my symptoms come back, slowly. I was on it for 2 months and I got super sick and had to go to the ER now I have to wait for my Remicade transfusions. Also, I had a stool test and the pill was in my stool, the pill wasn't even disintegrating???

Regular Member

Date Joined Apr 2013
Total Posts : 342
   Posted 1/5/2018 6:11 PM (GMT -6)   
I had a bad reaction to the new generic. It is supposed to be exactly the same pill. I went back on to brand name Lialda and am still trying to get back to where I was before.
Prescribed Asacol hd 6pills a day - not currently taking any. Pills are on the shelf.
Prednisone for flares - Satan's pill
Uceris since March '13 with great success quit taking 7/29
Been on the Specific Carbohydrate Diet in the past did ONLY SCD & FT (6x's)
Currently on generic Lialda since Sept 17

Veteran Member

Date Joined Jun 2010
Total Posts : 2354
   Posted 1/5/2018 8:08 PM (GMT -6)   
I think Shire brand generic is pretty much the same as Lialda (it is the same company that makes Lialda) The pills look identical.
UC diagnosed in 2010 but had prob. in 2009
2 Lialda/day Rowasa nightly, periodic anucort supp, Cortifoam as needed(needed more than I would like)
VSL#3, slippery elm
Metamucil capsules
Trying Gluten free (why not!)
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