Posted 8/6/2017 7:36 AM (GMT -7)
You're best with a higher dosage of enema such as 4g. But using the 1g twice daily is better than once. Please ask your doc to get you on an oral mesalamine....if your UC is climbing, you need better coverage.
It's not guaranteed it will reach splenic flexure so don't make that a determining factor for your only med. It definitely willmgo past the sigmoid.
Keep in mind there are Pentasa enemas with 100ml liquid and the other mesalamines such as Salofalk, Rowasa and generic that are 60ml liquid. Foam enemas are available in the UK for sure, 1g dosage, and I wouldn't state it reaches the splenic flexure.
Were you completely off the enemas before this?
Feel better soon,