Can Uceris or Lialda actually cause loose stools?

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chikinnooodle
Regular Member


Date Joined Oct 2017
Total Posts : 47
   Posted 11/4/2017 9:27 AM (GMT -6)   
Before my recent diagnosis, I had only slightly loose stools and many other symptoms. Now I’m about 6 weeks into my medications and all of my symptoms are gone (cramping, bleeding, urgency), but my stools are softer than ever once a day or once every couple of days. Complete mush. Possible side effect of meds??

momto2boys
Veteran Member


Date Joined Jun 2013
Total Posts : 1980
   Posted 11/4/2017 11:04 AM (GMT -6)   
More likely from the flare itself. I find that the last thing Togo back to normal is stool firmness.
42 yrs old diagnosed with proctosigmoiditis 6/13/13
meds- 2 Lialda + sfRowasa every other night- supplements: probiotics (1 VSL3 cap, 1 culturelle and 1 reuteri) 1 gram krill Oil, 1TBSP p. seed powder, 2 g curcumin. Allegra for seasonal allergies as needed. Allergic to sulfites. Currently gluten/dairy free (except yogurt) and eating lots of RS.

quincy
Elite Member


Date Joined May 2003
Total Posts : 30674
   Posted 11/4/2017 1:12 PM (GMT -6)   
Can......but misunderstood that some of us are undermedicated or actually overmedicated based on initial tolerance, only on oral or rectal without full coverage of 5ASA meds.

The flare is the fact....and inflammation increase and healing based on how much and location are more complicated regarding stool consistency. Add food into the mix, which can change consistency and increase or decrease.....

Try not to focus on the singular issues. With experience....you will start to understand the whole process.

Are you on rectal meds?

q
*Heather* I give suggestions, do with them what you will.
Status: ...Asacol 3 @ 2x daily; Salofalk enema @ 3rd night (nightly/ flares, tapered/maintenance)
~diagnosed January 1989 UC (proctosigmoiditis)
~Bentylol 20mg as needed; Zantac 150mg; Pulmicort/Airomir (asthma); Effexor XR 75mg (depression); Rosuvastatin 10mg (cholesterol); Telemesartin 80mg / Amlodipine 5mg (BP)
~vitamins/minerals/supplements; Probiotics....(RenewLife Ultimate Flora Critical Care + Genuine Health Advanced Gut Health 15 billion @ bedtime)
~Metamucil capsules 6 @ 2x daily with meals; Vitamin D 4500 IU
~URSO 500mg @ 2x daily for Primary Biliary Cholangitis
"TREAT (FROM)BOTH ENDS" worth it !!

chikinnooodle
Regular Member


Date Joined Oct 2017
Total Posts : 47
   Posted 11/4/2017 2:56 PM (GMT -6)   
I’m not on rectal meds. Currently feeling great, just really really soft stools. Softer than when I actually felt like I was flaring.

iPoop
Forum Moderator


Date Joined Aug 2012
Total Posts : 12727
   Posted 11/4/2017 6:09 PM (GMT -6)   
With uc, our days of perfectly predictable, and consistent poop logs are over lol. Even in a remission, my bms bounce around in fimness from solid to slightly soft. Consistency varies a lot with uc, it's perfectly normal, and nothing at all to worry about.

Ypu can take a fiber supplement like metamucil to firm things up and have greater consistency.
Moderator Ulcerative Colitis
John
, 39, UC Proctosigmoiditis
Rx: Remicade @5mgs/kg/6wks; daily 75mgs 6MP, 4.8g generic-Lialda, and rowasa

Urgency Roused "Oh the places I've pooed from culverts to shady bathrooms" the memoirs of a UC patient. Run, don't walk, to you local bookstore...

still_living
Regular Member


Date Joined Jan 2017
Total Posts : 45
   Posted 11/10/2017 1:14 PM (GMT -6)   
Hi there!

Its so hard to say what the loose stools are coming from.

For me, I DO feel like my Delzicol(mesalamine) MAY cause somewhat looser stools. I also know that my UC also causes looser stools too...so I have to be realistic when thinking I figured something out, that maybe I could be wrong.
That said, when I reduced my dosage from the higher 'remission' dose to the lower 'maintenance' dose my stools firmed up for a little while. Another thing I often have to consider it that with more inflammation is more swelling in my colon, and the beginning of a mini-flare can also involve some beautiful solid stools because things are slowing down, and therefore drying out for mechanical reasons. And that may well have been the case when I reduced my dose, too.

I think what I (and some of the others here) are trying to say, is that the likelihood its the UC is higher than if it possibly being the medication. But diarrhea and loose stool ARE on the list of mesalamine side effects, and in my experience it seems like for sure it can.

I've found it most beneficial to gauge my progress on more of a month by month basis rather than day to day. My meds took a long time to really kick in, and almost a year later, I still feel like I'm progressing and feeling better each month. At the same time though, I realize by body just functions differently, and probably if its not one thing its another with this disease. I don't expect to ever be be completely free from its effects. I'd take loose stools every day if that was the only complaint. (even if it was caused by meds lol)
29yo f
Dx Jan '17, mod left side UC with severe joint flares
Meds: Delzicol 2.4mg/d
Supp: multi-vit, turmeric/curcumin, boswellia helps most w/ joints, triphala, mj
Diet: yogurt, grains are a problem. definite coffee addict

chikinnooodle
Regular Member


Date Joined Oct 2017
Total Posts : 47
   Posted 6/11/2018 11:25 AM (GMT -6)   
This was originally my post and now that I am back on a higher dosage of Lialda and Uceris, my poop is very very mushy again. I wanted to ask if it seems normal that it is also on the more yellow side than brown?
Diagnosed Aug 2017, mild UC activity
Current meds: 2xLialda daily
No diet modifications.

quincy
Elite Member


Date Joined May 2003
Total Posts : 30674
   Posted 6/11/2018 12:12 PM (GMT -6)   
More yellow could be faster moving through colon, food intake, less bile in digestive tract, flaring.

How many times a day are you going?
Yellow in toilet or on tp?

q
*Heather* I give suggestions, do with them what you will.
Status: ...Asacol 3 @ 2x daily; Salofalk enema @ 3rd night (nightly/ flares, tapered/maintenance)
~diagnosed January 1989 UC (proctosigmoiditis)
~Bentylol 20mg as needed; Zantac 150mg; Pulmicort/Oxeze/Airomir (asthma); Effexor XR 75mg (depression); Rosuvastatin 10mg (cholesterol); Telemesartin 80mg / Amlodipine 5mg (BP)
~vitamins/minerals/supplements; Probiotics....(RenewLife Ultimate Flora Critical Care + Genuine Health Advanced Gut Health 50 billion @ bedtime)
~Metamucil capsules 6 @ 2x daily with meals; Vitamin D 4500 IU
~URSO 500mg @ 2x daily for Primary Biliary Cholangitis
"TREAT (FROM)BOTH ENDS" worth it !!

chikinnooodle
Regular Member


Date Joined Oct 2017
Total Posts : 47
   Posted 6/11/2018 1:02 PM (GMT -6)   
Generally only once every morning. I had either a bug or ate something bad 2 weeks ago so I’ve just been “off” since then, but my stool is generally more on the yellow side. In toilet and on toilet paper.
Diagnosed Aug 2017, mild UC activity
Current meds: 2xLialda daily
No diet modifications.

Sara14
Veteran Member


Date Joined Mar 2007
Total Posts : 4363
   Posted 6/11/2018 1:11 PM (GMT -6)   
It has been 11 years since I have had a pre-medicated poop, but I also believe that Asacol (now called Delzicol) changed the consistency of my stools to be more mushy. It could also be a flare symptom, so it is hard to say with certainty what the issue is for you. But if that is your only symptom, I would say it isnt anything to worry about.
34 years old; diagnosed March 2007.
Latest scope: 9-29-16: mild-to-moderate chronic and active proctosigmoiditis (infectious cause). Battled reoccuring campylobacter & c diff. Oct-Dec 2016. Healthy since Dec. 25, 2016 until I started smoking May 2018.
Current meds: Delzicol, 6, 2xday; Rowasa nightly; singular and Allegra for allergies; Xanax.

Adventureuc
Regular Member


Date Joined Apr 2013
Total Posts : 342
   Posted 6/11/2018 1:24 PM (GMT -6)   
Yes, I had that experience with Lialda. It worked for about a week or two then symptoms returned.
Prescribed Asacol hd 6pills a day - not currently taking any. Pills are on the shelf.
Prednisone for flares - Satan's pill
Uceris since March '13 with great success quit taking 7/29
Been on the Specific Carbohydrate Diet in the past did ONLY SCD & FT (6x's)
Currently on generic Lialda since Sept 17
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