Pentasa and pregnancy

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New Member

Date Joined Dec 2017
Total Posts : 1
   Posted 12/7/2017 9:35 PM (GMT -6)   
Hello, I'm new to the community. I was diagnosed with ulcerative colitis this past August but had symptoms for 2 years prior. I just had a baby in April, and had a small flare at the beginning of the pregnancy and at the end of the pregnancy. It got so bad I almost died sad

Anyways I'm currently on 4g of pentasa a day and i was told by my gastro that it's perfectly safe to take pentasa during pregnancy. It still worries me to take any medication while pregnant and I'm super nervous to take them if we try for another baby. Has anyone taken pentasa throughout their pregnancy and had no complications for the baby?

Forum Moderator

Date Joined Aug 2012
Total Posts : 12781
   Posted 12/8/2017 8:11 AM (GMT -6)   
Welcome to the forum!

We've had a number of moms take Pentasa while pregnant and have happy and healthy babies without issues. Pentasa is a mild, 90% topical, anti-inflammatory medication and well tolerated by most. It's important for mom to be healthy during the pregnancy to have the best outcome for her baby, so I would strongly recommend taking your medications throughout your pregnancy. You're more likely to have complications by foregoing the meds and causing a UC flareup.

Here's a couple links from our Resources section that you might find helpful:

From conception to delivery: Managing the pregnant inflammatory bowel disease patient

The Second European Evidenced-Based Consensus on Reproduction and Pregnancy in Inflammatory Bowel Disease
Moderator Ulcerative Colitis
, 39, UC Proctosigmoiditis
Rx: Remicade @5mgs/kg/6wks; daily 75mgs 6MP, 4.8g generic-Lialda, and rowasa

U.C. = Unimaginable Crapnado

Veteran Member

Date Joined Mar 2007
Total Posts : 1757
   Posted 12/8/2017 5:53 PM (GMT -6)   
iPoop is right. The risk from most of the UC medications to the unborn baby is minimal, if not outright nonexistent. The greater risk is if the mother flares while pregnant. Mothers with UC are known to be higher risk pregnancies (low birth weight, early delivery, etc), but that's from the disease itself, not from the treatments. The main goal for a pregnant mother with UC is to keep the disease under control. Flares of disease during pregnancy increase risk of problems far more than the medications do.

The exception to all this is methotrexate, which must be avoided if even considering pregnancy.
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