From all the research I've done over the years, it seems that the vast majority of UC is brought on by either antibiotics or bacterial gut infection. The rates of IBD in the developed world are probably increasing because industrial farming is causing more contaminated food with stronger organisms that are antibiotic resistant. Even sub-clinical infections that don't tend to bother people can cause IBD because the organisms penetrate the gut barrier and cause immune sensitization. It's why even healthy people can suddenly get IBD now -- it's because the organisms are stronger, produce more powerful endotoxins, and are more invasive.
The rat models show us that rats born in a sterile environment and completely lacking gut bacteria do not develop IBD.
The medical establishment is tip-toeing around the fact that food contamination is the reason for the disease because to admit to this would be to
open a huge can of worms on the whole pharmaceutical-food complex. There was always IBD but the rates have skyrocketed since the mid 20th century when the Green Revolution started and we all started eating nutrient deficient, antibiotic and chemical laden food. Now add super bugs to the picture and of course people's guts are eroding. And it's no secret that for many, the treatment or even the reason for their remission is a reversion to an organic, nutrient rich, whole food diet.
The developing world has lower rates than us because they are still largely relying on traditional food systems and agriculture that do not create any of these problems.
Post Edited (Connor77) : 12/25/2017 5:59:08 PM (GMT-7)